CAS: 14316-16-6; N-(2-Aminoethyl)-4-Methylbenzenesulfonamide

相似化合物

18807-71-1 333-18-6 4152-09-4

上下游产品

CAS号107-15-3 乙二胺 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号3634-89-7 N-甲苯磺酰基氮杂环丙烷 | CAS号6331-00-6 N-(2-chloroethy... | CAS号4556-90-5 N-(2-bromoethyl... | CAS号14316-14-4 N-(2-羟乙基)-4-甲基苯磺酰胺 | CAS号1153-45-3 4-甲基苯磺酸-4-硝基苯酯

N-甲苯磺酰基氮杂环丙烷置于palladium On Activated Charcoal 叠氮基三甲基硅烷,四丁基氟化铵,氢气体系中,用 四氢呋喃,甲醇 用作溶剂,化学反应 32.0H,反应生成N-甲苯磺酰基乙二胺
参考文献:氮丙啶与三甲基甲硅烷基化合物的有效开环反应:轻松获得β-氨基酸和1,2-二胺衍生物
标题:氮丙啶与三甲基甲硅烷基化合物的有效开环反应:轻松获得β-氨基酸和1,2-二胺衍生物
摘要:由四丁基氟化铵引发的氮丙啶与三甲基甲硅烷基化合物的开环反应以极好的收率选择性地产生相应的产物.它为氮丙啶的开环反应提供了一种简便而有效的方法,并且由于其效率和简便性,为氰基,叠氮基或氯胺的合成提供了实用途径.该产物容易转化为邻位二胺或β-氨基酸.
Doi:10.1021/jo9913816

专利信息

专利号:US-8765668-B2
优先权日:2010-06-04
标 题 :Methods of synthesis of β-aminobutyryl substituted compounds
发明人：STERK DAMJAN; USTAR MATJAZ; ZLICAR MARKO
权利人:STERK DAMJAN; USTAR MATJAZ; ZLICAR MARKO; LEK PHARMACEUTICALS
摘要:The present invention relates to process to prepare β-aminobutyryl compounds having β-amino acid core structural moieties and optionally having γ-phenyl and/or heterocyclic structural moieties. Such compounds are useful as key structure framework of modern drug chemistry.

专利号:US-8471023-B2
优先权日:2009-06-11
标 题:Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer
发明人：GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W
权利人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W; MALLINCKRODT LLC
摘要:The present invention provides processes for the stereoselective synthesis of 6-alpha-amino morphinans. In particular, the invention provides processes for the reductive amination of 6-keto normorphinans by catalytic transfer hydrogenation.

专利号:US-8415474-B2
优先权日:2009-09-24
标题 :One-pot preparation of hexahydroisoquinolines from dihydroisoquinolines
发明人：GROTE CHRISTOPHER W; MOSER FRANK W; WANG PETER X; CANTRELL GARY L; BERBERICH DAVID W
权利人:GROTE CHRISTOPHER W; MOSER FRANK W; WANG PETER X; CANTRELL GARY L; BERBERICH DAVID W; MALLINCKRODT LLC
摘要:The present invention provides an efficient process for the preparation of hexahydroisoquinolines from dihydroisoquinolines. In particular, the invention provides a good yielding, one-pot process for the synthesis of hexahydroisoquinolines.

专利号:US-8519133-B2
优先权日:2009-06-11
标 题 :Preparation of 6-alpha-amino N-substituted morphinans by catalytic hydrogen transfer
发明人：GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W
权利人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W; MALLINCKRODT LLC
摘要:The present invention provides processes for the stereoselective synthesis of 6-alpha-amino N-substituted morphinans. In particular, the invention provides processes for the reductive amination of 6-keto N-substituted morphinans by catalytic hydrogen transfer.

专利号:US-8921561-B2
优先权日:2009-09-24
标题 :One-pot preparation of hexahydroisoquinolines from amides
发明人：GROTE CHRISTOPHER W; MOSER FRANK W; WANG PETER X; CANTRELL GARY L; BERBERICH DAVID W
权利人:MALLINCKRODT LLC
摘要:The present invention provides an efficient process for the preparation of hexahydroisoquinolines from amides. In particular, the invention provides a good yielding, one-pot process for the synthesis of hexahydroisoquinolines.

专利号:US-2013102730-A1
优先权日:2010-04-02
标 题:Polyamine-containing polymers and methods of synthesis and use
发明人：JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).