CAS: 132413-50-4; 2,3,4,6-Tetra-O-Benzoyl-β-D-Glucopyranosyl Isothiocyanate [for Hplc Labeling]
该化合物是一种甘醇基捐献物衍生物,广泛用于碳水化合物化学合成硫柳汞和甘醇基甲酸酯,苯基保护组增强了稳定性,有利于选择性的相合反应,而异硫氰酸盐混合物为与胺或其他核糖核素结合提供了反应处理器,该化合物对于在温和条件下建立甘醇联系,提供高视象选择性和立体控制,尤其有用.其效用扩大到制备甘基基硫酸盐和其他生物活性分子.晶体固态保证了处理和储存的便利,使其成为医药化学和精密研究中合成应用的可靠试剂.
- 英文名称2,3,4,6-Tetra-O-Benzoyl-β-D-Glucopyranosyl Isothiocyanate [for Hplc Labeling]
- 中文名称2,3,4,6-四-O-苯甲酰基-β-D-吡喃葡萄糖基异硫氰酸酯[用于高效液相色谱标记]
- IUPAC名称(2R,3R,4S,5R,6R)-2-((benzoyloxy)methyl)-6-isothiocyanatotetrahydro-2H-pyran-3,4,5-triyl tribenzoate
- 其它别名2,3,4,6-四-O-苯甲酰基- β-D-吡喃葡萄糖基异硫氰酸酯[用于高效液相色谱标记]; 2,3,4,6-Tetra-O-Benzoyl-Beta-D-Glucopyranosyl Isothiocyanate [for Hplc Labeling]
- CAS编号132413-50-4
- MFCD编号:MFCD00075064
- EINECS号:631-353-4
- 分子式:C35H27NO9S分子量:637.67
- 产品CID: 490078
- 产品分类有机原料→生命科学→生化试剂→碳水化合物
相似化合物
183901-63-5 627466-84-6 286369-05-9物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
急性毒性 类别4(吸入)
急性毒性 类别4(经口) - 警示词Warning(警告)
- 危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H332 |吸入有害.
H302 |吞咽有害. - 防范说明P260-P261-P264-P271-P272-P273-P280-P284-P302+P352-P304+P340-P362+P364-P405-P501
- 危险等级6.1
- UN编号2811.0
- 危险品标志Xi
- 包装等级Ⅲ
- 安全声明26-36/37/39
- 危险类别码36/37/38
- WGK Germany3
欧盟法规
C&L通报上下游产品
CAS号333-20-0 硫氰酸钾 | CAS号61198-88-7 per-O-benzoyl-α... | CAS号98-88-4 苯甲酰氯 | CAS号22435-65-0 N-(2,2-diethoxy... | CAS号463-71-8 硫光气 | CAS号108967-43-7 2,3,4,6-tetra-O... | CAS号158419-90-0 2,3,4,6-tetra-O...合成工艺路线路线简述
- 333-20-0 + 14218-11-2 + 866013-58-3 = 132413-50-4 + 158419-88-6
反应条件:1.1S:Me2Co,24 H,Rt2.1S:Ch2Cl2,20 H,20°C
标题:Influence Of Bromide Ions On The Synthesis Of Anomeric Thiocyanates
作者:By Cmoch,Piotr And Pakulski,Zbigniew
参考文献:Tetrahedron 日期:2012 卷标:68(36) 页码:7435-7440]
333-20-0 + 14218-11-2 = 132413-50-4 + 158419-88-6
反应条件:1.1C:18-Crown-6,S:Me2Co
标题:Studies Into The Preparation Of 1-Deoxy-1-Thiocyanato-D-Glycopyranosyl Cyanides And The Anomeric Effect Of The Thiocyanate Group
作者:By Somsak,L. Et Al
参考文献:Tetrahedron: Asymmetry 日期:2001 卷标:12(5) 页码:731-736
📜2,3,4,6-Tetra-O-Benzoylglucosyl Bromide置于18-冠醚-6,Potassium Thioacyanate体系中,用 丙酮 用作溶剂,化学反应 9.0H,反应生成2,3,4,6-四-O-苯甲酰基-β-D-吡喃葡萄糖基异硫氰酸酯
参考文献:Studies Into The Preparation Of 1-Deoxy-1-Thiocyanato-D-Glycopyranosyl Cyanides And The Anomeric Effect Of The Thiocyanate Group
标题:Studies Into The Preparation Of 1-Deoxy-1-Thiocyanato-D-Glycopyranosyl Cyanides And The Anomeric Effect Of The Thiocyanate Group
摘要:The Reaction Of Per-O-Acetylated 1-Bromo-1-Deoxy-Alpha-D-Arabinopyranosyl Cyanide With Thiocyanate Ions Gave The Corresponding 1-Deoxy-1-Thiocyanato-Alpha-And Beta-D-Arabinopyranosyl Cyanides. In The Reaction Of The Per-O-Acetylated 1-Bromo-1-Deoxy-Beta-D-Xylopyranosyl Cyanide And Its Per-O-Benzoylated Beta-D-Glucopyranosyl Analogue The Corresponding 2-Hydroxy-Glycal Esters Formed In Addition To The Anomeric Pair Of Thiocyanato-Cyanides. The Formation Of 2,3,4,6-Tetra-O-Benzoyl-Alpha-D-Glycopyranosyl Thiocyanate Was Demonstrated In The Reaction Of Benzobromoglucose With Thiocyanate Ions. The Equilibrium Constant Between 2,3,4,6-Tetra-O-Acetyl-1-Deoxyl-1-Thiocyanato-Alpha-And Beta-D-Galactopyranosyl Cyanides Was Determined. Based On This Value,The Equilibrium Ratio For The 2.3.4,6-Tetra-O-Acetyl-Alpha-And Beta-D-Galactopyranosyl Thiocyanates Was Calculated To Be 94:6,And The Anomeric Effect Of The Scn Group Was Estimated To Exceed 3 Kcal/mol. X-Ray Crystallographic Data Support Endo-And Exo-Anomeric Effects Of The Scn Moiety. (C) 2001 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0957-4166(01)00112-4
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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合成参考文献
参考DOI号:10.1016/S0040-4020(01)87009-5
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