CAS: 79516-68-0; (3S,4R)-1-[4-Cyano-4-(4-Fluorophenyl)Cyclohexyl]-3-Methyl-4-Phenylpiperidine-4-Carboxylic Acid
- 英文名称(3S,4R)-1-[4-Cyano-4-(4-Fluorophenyl)Cyclohexyl]-3-Methyl-4-Phenylpiperidine-4-Carboxylic Acid
- 中文名称左卡巴司丁
- IUPAC名称(3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
- 其它别名4-Piperidinecarboxylicacid, 1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-,[3S-[1(cis),3a,4b]]-; Lev°Cabastine; Levophta
- CAS编号79516-68-0
- MFCD编号:MFCD00672639
- 分子式:C26H29FN2O2分子量:420.52
- 产品CID: 1789518
- 产品分类原料药 → 抗变态反应药 → 抗组胺药
物理性质
- 沸点589.9 °C at 760 mmHg
- 闪点310.5 °C
- 密度1.23 g/cm3
- pKa:3.57±0.40(预测)
- PSA:64.33
- LogP:4.83198
- 折射率1.606
- 外观形态固体-粉末
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用左卡巴斯汀(79516-68-0)的用途:组胺H1受体拮抗剂,选择性高,活性强.用于过敏性鼻炎,过敏性结膜炎.左卡巴斯汀(79516-68-0)的功能主治:用于过敏性疾病的治疗.
- 性质描述左卡巴斯汀(79516-68-0)的化学性质:盐酸左卡巴斯汀:C26H29FN2O2.HCl.结晶,熔点298-299°C.
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905121000-正丙醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Akiyoshi M, Shigeoka T, Torii S, Maki E, Enomoto S, Takahashi H, Hirano F. [Pharmacological and clinical properties of levocabastine hydrochloride (eye drop and nasal spray), a selective H1 antagonist]. Nihon Yakurigaku Zasshi. 2002 Mar;119(3):175-84. Review. Japanese. Review. Review. Review. Review. Review. Review. Review. Review. Review.
📝 需求与反馈
尽可能描述清楚需求与问题信息
