专利号:US-2009264648-A1 优先权日:2008-01-14 标题:Synthesis of pyrazoles 发明人:CHEW WARREN; WANG ZHENG; CHEAL GLORIA; BERTRAND MARTIAL; POTOSKI JOHN; MIRMEHRABI MAHMOUD; NENCINI ARIANNA; ZANALETTI RICCARDO 权利人:WYETH CORP; SIENA BIOTECH SPA 摘要:The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
专利号:US-11312722-B2 优先权日:2019-05-08 标 题:Hsp90 inhibitors and uses thereof 发明人:BROWN LAUREN ELAINE; HUANG DAVID S; COWEN LEAH E; WHITESELL LUKE; MARCYK PAUL 权利人:UNIV BOSTON; GOVERNING COUNCIL UNIV TORONTO 摘要:Herein is described the design and synthesis of resorcylate aminopyrazole compounds. These compounds show broad, potent and fungal-selective Hsp90 inhibitory activity. These compounds also find use in treating Hsp90 related diseases.
专利号:RU-2047604-C1 优先权日:1990-07-21 标题 :Substituted azoles and a method of their synthesis