CAS: 72-54-8; Ddd

该化合物是一种有机氯化合物,属于农药家族,是滴滴涕(二氯二苯三氯乙烷)的衍生物,主要用于杀虫性能;p,p-DDD的化学结构具有两个苯环,由二氯乙醇桥连接,有助于其稳定和持久性,其特点是其在水中的溶性较低,但在有机溶剂中具有高溶性,因此它具有脂性.p,po-DCD因在环境中的长半衰期而闻名,导致食物链中的生物累积,它表现出内分泌干扰特性,可能影响野生生物和人类健康;由于这种化学结构的环境持久性和潜在的健康风险,许多国家限制或禁止使用p,P,P-D DDD.在处理该物质时,必须采取安全措施,因为它可能构成吸入,皮肤接触或摄入等风险.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

diethyl ether p,p'-DDT ethanol dichloroacetaldehyde diethyl acetal 1-chloro-2,2-bis(p-chlorophenyl)ethylene 1,1-bis(4-chlorophenyl)ethane 4,4'-dichlorostylbene bis(4-chlorophenyl)acetylene

合成工艺路线路线简述

  • 合成目标产物 P,P'-Ddd 主要起始原料 4,4'-Ddt
  • (文献来源)合成步骤主要原料 4,4'-Ddt
📜2,2-二氯-1-(4-氯苯基)乙酮置于硫酸,异丙醇体系中,化学反应生成 2,2-双(对氯苯基)-1,1-二氯乙烷
参考文献:The Chemical Composition Of Technical Ddt1
标题:The Chemical Composition Of Technical Ddt1
摘要:
DOI:10.1021/ja01225A058

海关参考信息

专利信息


专利号:US-6770436-B1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays
发明人:BEECHER JODY E; GOLDBERG MARTIN J; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:Radiation-activated catalysts (RACs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers. When irradiated, RACs produce catalysts that can react with enhancers, such as those involved in autocatalytic reactions. The autocatalytic reactions produce at least one product that removes protecting groups from synthesis intermediates. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.

专利号:US-2004110133-A1
优先权日:2002-12-06
标 题 :Functionated photoacid generator for biological microarray synthesis
发明人:XU GUANGYU; GOLDBERG MARTIN
权利人:AFFYMETRIX INC
摘要:In some embodiment of the invention, methods are provided for the synthesis of polymer arrays. In one embodiment, a chemically amplified polymer matrix is used for the synthesis of polymer arrays.

专利号:US-7053198-B2
优先权日:2002-12-06
标题 :Functionated photoacid generator and functionated polymer system for biological microarray synthesis
发明人:GOLDBERG MARTIN; XU GUANGYU
权利人:AFFYMETRIX INC
摘要:In some embodiment of the invention, methods are provided for the synthesis of polymer arrays. In one embodiment, a reactive polymer and a photo acid generator is used for the photodirected polymer array synthesis.

专利号:US-2004203056-A1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays

专利号:US-2006141511-A1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays

专利号:WO-9820967-A1
优先权日:1996-11-14
标 题:Chemical amplification for the synthesis of patterned arrays

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主要参考文献


1: Cobourn K, Fayed I, Keating RF, Oluigbo CO. Early outcomes of stereoelectroencephalography followed by MR-guided laser interstitial thermal therapy: a paradigm for minimally invasive epilepsy surgery. Neurosurg Focus. 2018 Sep;45(3):E8. doi: 10.3171/2018.6.FOCUS18209. doi: 10.1016/j.cryobiol.2018.08.011. Epub 2018 Aug 24. doi: 10.1186/s12934-018-0976-x.
4: Çanga Y, Emre A, Yüksel GA, Karataş MB, Yelgeç NS, Gürkan U, Çalık AN, Tireli H, Terzi S. Assessment of Atrial Conduction Times in Patients with Newly Diagnosed Parkinson's Disease. Parkinsons Dis. 2018 Jul 16;2018:2916905. doi: 10.1155/2018/2916905. eCollection 2018.
5: Hubig M, Muggenthaler H, Schenkl S, Mall G. Temperature-based death time estimation in near equilibrium: Asymptotic confidence interval estimation. Forensic Sci Int. 2018 Sep;290:189-195. doi: 10.1016/j.forsciint.2018.07.010. Epub 2018 Jul 20. doi: 10.1016/j.micpath.2018.07.045. [Epub ahead of print] doi: 10.1038/s41598-018-29022-4.

合成参考文献


摘要:Quarterly Bulletin--Association of Food and Drug Officials of the United States., 16(3), 1952
摘要:Laboratory Animal Science., 26(274), 1976 []
摘要:Meister, R.T., Sine, C; Crop Protection Handbook Volume 94. Meister Media Worldwide, Willoughby, OH 2008, p. D 413
摘要:40 CFR 302.4 (USEPA); U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of April 22, 2009:
摘要:Murty, A.S. Toxicity of Pesticides to Fish. Volumes I, II. Boca Raton, FL: CRC Press Inc., 1986., p. V2 62
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