CAS: 4214-28-2; 4-Iodo-M-Xylene

上下游产品

m-xylene 2,4-Xylidine o-xylene nitric acid 3-iodanediyl diacetate(2,4-dimethylphenyl)-λ3-iodanediyl diacetate (ph-2,4-me2)Si(Oet)3 4,6,2',4'-tetramethyl-biphenyl-2-sulfonic acid phenyl ester 4,6-diiodo-1,3-xylene

2,4-Dimethylbenzenediazonium Tetrafluoroborate置于potassium Iodide体系中,用 水 作为反应溶剂,化学反应 0.08H,以84%的收率获得产物2,4-二甲基-1-碘苯
参考文献:在温和的条件下,由重氮氟硼酸芳酯在水中高效合成芳基碘化物
标题:在温和的条件下,由重氮氟硼酸芳酯在水中高效合成芳基碘化物
摘要:已经描述了在温和条件下从水中的重氮杂氟硼酸芳基化合物的无过渡金属合成有价值的芳基碘化物.在目前的反应条件下,以定量产率(> 99%)获得了大部分合成的芳基碘化物.由于存在于芳基重氮氟硼酸酯上的取代基而引起的结构效应对芳基碘化物的产率没有显示出令人满意的效果.因此,发现这里提出的方法对于定量生产合成有价值的芳基碘是不定的.
DOI:10.2174/1570178614666170907120329

专利信息

专利号:US-6419814-B1
优先权日:2000-11-02
标 题:Methods for electrochemical synthesis of organoiodonium salts and derivatives
发明人：PLETCHER DEREK; WEINBERG NORMAN L
权利人:CORNELL DEV LLC
摘要:Organoiodonium salts, including certain novel symmetrical and unsymmetrical diaryliodonium;. polyiodonium and cyclic iodonium salts are synthesized by a significantly improved electrochemical coupling reaction which provides greater control and selectivity over the end product produced. Reaction mixtures comprising aryliodides and/or aromatic substrates are electrolyzed in novel reaction mediums comprising strong acid electrolyte, lower carboxylic acid, and preferably in the presence of acid anhydride in amounts >10 percent by-weight, and up to 50 percent by-weight or more, to provide a high degree of product selectivity, and at yields which can even be quantitative. The methods are conducted by introducing the electrolysis reaction mixture into an undivided electrochemical cell equipped with a cathode and preferably a conductive carbon anode. A voltage is applied across the electrodes to electrolyze the reaction mixture to generate selectively mainly iodonium cation, or if desired, only aryliodide esters, at the anode.

专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.

专利号:CN-113087691-B
优先权日:2021-03-26
标题:A method for the synthesis of chiral aryl tertiary alcohols and benzopyrans based on a kinetic resolution strategy

专利号:CN-106458943-A
优先权日:2014-04-07
标 题:Synthesis of Vortioxetine via (2,4-Dimethylphenyl)(2-iodophenyl)sulfane Intermediate

专利号:WO-2021146391-A1
优先权日:2020-01-16
标 题:Reagents and their use for modular enantiodivergent synthesis of c–p bonds

专利号:EP-2930171-A1
优先权日:2014-04-07
标 题:Synthesis of vortioxetine via (2,4-dimethylphenyl)(2-iodophenyl)sulfane intermediate