CAS: 39098-85-6; 3-Oxobutanoyl Chloride

该化合物是氯丙烷,其功能组和结构特征为丙烯,其产物为丁诺酸,在碳的第三个位置上有一个氯酮组.该化合物一般是无色的,可粉黄液,具有刺破的气味,表明其反应性.作为氯乙烷,其反应性很强,特别是水,酒精和胺,导致形成相应的酸,酯和胺.由于该物质具有腐蚀性,而且有可能在水解过程中释放盐酸,因此必须谨慎处理该物质.在合成有机化学中,丁诺基氯化物,3氧化物是合成各种有机化合物的重要中间体,包括制药和农用化学物.该物质具有反应性,并且能够参与熔化反应,因此在化学合成中成为有价值的试剂.适当的安全措施,包括使用个人防护设备和在烟雾头中工作,在与该化合物合作时至关重要.

结构式图片

MSDS等安全信息

    上下游产品

    CAS号674-82-8 双乙烯酮 | CAS号93-91-4 1-苯基-1,3-丁二酮 | CAS号88121-68-0 (3R,4R)-3-acety... | CAS号81375-55-5 6-methyl-2-phen... | CAS号691-45-2 but-1-ene-1,3-dione | CAS号520-45-6 脱氢乙酸

    合成工艺路线路线简述

      📜双乙烯酮置于盐酸体系中,用 甲苯 用作溶剂,化学反应 3.0H,反应生成3-氧代丁酰氯
      参考文献:碳酸钠作为生成乙炔酮的固相试剂
      标题:碳酸钠作为生成乙炔酮的固相试剂
      摘要:3-氧代丁酰氯(14)的甲苯溶液与na 2 Co 3在催化量的三乙胺的存在下,在-78oc下反应,生成乙酰基乙烯酮(2)溶液,将其二聚体分离出来.乙炔酮(2)被2-丙酮,2-丙醇和乙基乙烯基醚捕集.
      Doi:10.1016/j.Tetlet.2009.01.008

      海关参考信息

      专利信息


      专利号:US-6933385-B2
      优先权日:2001-08-03
      标题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
      发明人:WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
      权利人:SCHERING AG
      摘要:The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

      专利号:US-2003158412-A1
      优先权日:2001-08-03
      标 题:Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use

      专利号:US-2003149281-A1
      优先权日:2001-08-03
      标 题:Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production

      专利号:US-6521780-B1
      优先权日:1996-03-15
      标题 :Cycloalkyl derivatives and the solid-phase synthesis of such derivatives
      发明人:TIETZE LUTZ F; STEINMETZ ADRIAN
      权利人:BASF AG
      摘要:The invention relates to cycloalkyl derivatives, a process for their preparation and their use

      专利号:US-7034165-B2
      优先权日:2001-08-03
      标 题 :Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production

      专利号:CN-115925616-A
      优先权日:2022-11-21
      标题:A kind of green synthesis method of lercanidipine hydrochloride

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      合成参考文献


      摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
      摘要:Kollenz, G.; Ebner, S., Science of Synthesis, (2006) 23, 272.
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