CAS: 26555-40-8; Hypochlorous (Methyl Carbonic) Thioanhydride

该化合物是一种反应性硫化合物,主要用作有机合成的多功能中间体. 它的主要优点包括能够作为硫化物剂,促进将甲氧基碳基磺酰基(-SC(O) OCH3) 引入各种子体. 这个功能在合成硫乙基循环,制药和农用化学物方面很有价值. 化合物的高再活动使得在温和条件下进行高效的转化, 使之适合对复杂分子进行选择性的修改. 妥善处理由于其湿度敏感度和潜在腐蚀性, 至关重要. 它的应用扩大到了硫化物化学和聚合物的修改, 在需要受控硫化的情况下.

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物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号67-56-1 甲醇 | CAS号2757-23-5 氯羰基亚磺酰氯 | CAS号463-58-1 羰基硫 | CAS号68617-64-1 3-(2-吡啶二硫代)丙酸 | CAS号88766-27-2 methyl (methoxy... | CAS号88766-28-3 methyl (methoxy... | CAS号88766-25-0 methyl (methoxy... | CAS号88766-58-9 S-(N-methylanil...

合成工艺路线路线简述

    📜氯羰基亚磺酰氯 以 甲醇 用作溶剂,化学反应生成氯化甲氧羰基硫
    参考文献:Labeling Nucleic Acids
    标题:Labeling Nucleic Acids
    摘要:用于核酸多步标记的试剂和方法允许在最后一步向核酸添加相对不溶解或不稳定的标记物.核酸可以作为一个稳定的中间体储存,能够与连接到巯基反应性基团的标记物发生反应.

    海关参考信息

    专利信息


    专利号:US-12144874-B2
    优先权日:2015-09-09
    标题 :Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
    发明人：KULARATNE SUMITH A; GAGARE PRAVIN
    权利人:ON TARGET LABORATORIES LLC; ON TARGET LABORATORIES INC
    摘要:The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria after compounds were delivered to diseased tissues such as cancer using a ligand that target receptor that express on the diseased tissue and followed by receptor mediated endocytosis and provide effective activity against cancer cells as well as other disorders. Methods and compositions for use of the same are described.

    专利号:US-10676487-B2
    优先权日:2015-09-09
    标 题 :Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
    发明人：KULARATNE SUMITH A; GAGARE PRAVIN; MYERS CARRIE H
    权利人:ON TARGET LABORATORIES LLC
    摘要:The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria after compounds were delivered to diseased tissues such as cancer using a ligand that target receptor that express on the diseased tissue and followed by receptor mediated endocytosis and provide effective activity against cancer cells as well as other disorders. Methods and compositions for use of the same are described.

    专利号:WO-2017044445-A1
    优先权日:2015-09-09
    标题 :Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer

    专利号:EP-3347010-A1
    优先权日:2015-09-09
    标题:Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer

    专利号:CN-108135885-A
    优先权日:2015-09-09
    标 题 :Synthesis and composition of photodynamic therapy agents for targeted treatment of cancer

    专利号:US-2025255991-A1
    优先权日:2015-09-09
    标 题 :Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer

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    ⚠️全国化工行业净网倡议书
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    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Christian Starkenmann, Et Al. Nonvolatile S-Alk(En)Ylthio-L-Cysteine Derivatives In Fresh Onion (Allium Cepa L. Cultivar). J Agric Food Chem. 2011 Sep 14;59(17):9457-65.
    [参考文献]: Mauricio F Erben, Et Al. Anomeric And Mesomeric Effects In Methoxycarbonylsulfenyl Chloride, Ch(3)Oc(O)Scl: An Experimental And Theoretical Study. Inorg Chem. 2002 Mar 11;41(5):1064-71.

    合成参考文献


    摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 203.
    摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 203.
    摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 203.
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