CAS: 22900-11-4; (2S,4S,5R,6R)-Methyl 5-Acetamido-2,4-Dihydroxy-6-((1R,2R)-1,2,3-Trihydroxypropyl)Tetrahydro-2H-Pyran-2-Carboxylate

相似化合物

73208-82-9 55717-54-9 50998-13-5

上下游产品

CAS号67-56-1 甲醇 | CAS号19342-33-7 (2S,4S,5S,6R)-5...

📜N-乙酰神经氨酸 以 甲醇 用作溶剂,以95%的收率获得n-乙酰神经氨酸甲酯
参考文献:Polyvalent Polymers For The Treatment Of Rotavirus Infection
标题:Polyvalent Polymers For The Treatment Of Rotavirus Infection
摘要:本发明包括包含富醣苷基团的可聚合单体.在一种实施方式中,该单体具有可聚合官能团,例如烯烃键,富醣苷基团通过间隔基团连接到其中,例如烷基基团,或其中一个或多个碳原子被杂原子(如氧,氮或硫原子)取代的烷基基团.本发明还包括包含一个或多个富醣苷基团的聚合物,例如挂链富醣苷基团,可以抑制或预防哺乳动物中的轮状病毒感染.这样的聚合物可以包括,例如,本发明的单体.该聚合物可以是同聚物或共聚物,并且可以具有例如聚丙烯酰胺,聚丙烯酸酯或聚苯乙烯骨架.在另一实施方式中,本发明包括一种治疗哺乳动物(例如人类)轮状病毒感染的方法,通过向哺乳动物施用包含一个或多个糖苷基团的聚合物的治疗有效量,例如挂链糖苷基团.这些糖苷基团可以是例如富醣苷基团或唾液酸基团.该聚合物可以是同聚物或共聚物.在一种实施方式中,该聚合物是包含一个糖苷基团单体和一个疏水性单体的共聚物.在另一实施方式中,要施用的聚合物包括两种或更多不同的糖苷基团单体.

专利信息

专利号:US-5837830-A
优先权日:1994-03-09
标 题 :Stereodirected process for synthesis of α-N-acetylgalactosaminides
发明人：KOGANTY RAO R; GANDHI SHAM
权利人:BIOMIRA INC
摘要:A stereodirected process for synthesizing alpha -N-acetylgalactosaminides from N-acetylgalactosamine which, in a preferred embodiment, comprises: reacting N-acetylgalactosamine with a dialkyl acetal of an aldehyde or ketone to form a 4,6-O-alkylidene derivative; reacting said 4,6-O-alkylidene derivative with a protecting group compound to attach a protecting group selectively to 3-OH of said derivative to form a 3-O-protected derivative; reacting said 3-O-protected derivative with an anomeric group to form a glycosyl donor; reacting said glycosyl donor with an alcohol to form an N-acetylgalactosaminide.

专利号:US-6844346-B2
优先权日:1997-10-27
标 题 :Chromogenic substrates of sialidase and methods of making and using the same
发明人：JOHNSON STEPHEN C; SAEED ASHRAF; LUO MING
权利人:IBBEX INC; UNIV OF ALABAMA AT BIRMINGHAM
摘要:The subject invention discloses materials and methods for the design, synthesis, and biochemical evaluation of chromogenic substrate compounds for sialidases of bacterial, viral, protozoa, and vertebrate (including humans) origin. These compounds are based upon N-acetylneuraminic acid glycosides. In particular, this invention provides a novel class of these compounds as chromogenic substrates of these sialidases which yield chromogenic products after reactions catalyzed by sialidase take place. Also provided are methods of making these substrate compounds, methods of diagnosis and prognosis of sialidase related diseases using these substrate compounds.

专利号:US-5527891-A
优先权日:1994-03-09
标题 :Stereodirected process for synthesis of α-N-acetylgalactosaminides

专利号:WO-9518186-A1
优先权日:1993-12-28
标 题 :Modular design and synthesis of aminimide containing molecules

专利号:US-9237764-B2
优先权日:2010-02-19
标题:Production of 6′-O-sialyllactose and intermediates
发明人：FIGUEROA PÉREZ IGNACIO; Horváth Ferenc; DEKANY GYULA; Ã?GOSTON KÃ?ROLY; Ã?GOSTON Ã?GNES; BAJZA ISTVÃ?N; BOUTET JULIEN; HEDEROS MARKUS; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS; RISINGER CHRISTIAN
权利人:FIGUEROA PÉREZ IGNACIO; Horváth Ferenc; DEKANY GYULA; Ã?GOSTON KÃ?ROLY; Ã?GOSTON Ã?GNES; BAJZA ISTVÃ?N; BOUTET JULIEN; HEDEROS MARKUS; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS; RISINGER CHRISTIAN; GLYCOM AS
摘要:The present invention relates to a method for preparation of the trisaccharide 6′-O-sialyllactose (formula (I)) or salts thereof as well as intermediates in the synthesis and for the use of 6′-O-sialyllactose salts in pharmaceutical or nutritional compositions.

专利号:EP-0737232-A4
优先权日:1993-12-28
标 题:MODULAR DESIGN AND SYNTHESIS OF AMINIMID-CONTAINING COMPOUNDS