CAS: 89604-92-2; (Z)-Tert-Butyl 2-(((1-(2-Aminothiazol-4-yl)-2-(Benzo[d]Thiazol-2-Ylthio)-2-Oxoethylidene)Amino)Oxy)-2-Methylpropanoate

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CAS号102772-66-7 头孢他啶叔丁酯

专利信息

专利号:WO-2005100378-A1
优先权日:2004-04-13
标 题:Process for the preparation of a peptide, and compounds comprising a thioester carboxyl-activating group for use therein
发明人：EVANS DAVID JOHN
权利人:AVECIA LTD; EVANS DAVID JOHN
摘要:There is provided a process for the solid-phase synthesis of a polymer which comprises reacting an amine, secondary amine or hydroxyl group of a first monomer with a thioester on a second monomer wherein at least one the monomers is immobilised on a solid-phase support. There is also provide novel activated amino acids of Formula (1) wherein: R is an amino acid side chain a protected amino acid side chain or a peptide chain; X is an amino protecting group; and Z is an optionally substituted hydrocarbyl, and certain supported activated amino acids of Formula (5) wherein: SUPPORT is a solid support; L is a linking group; R is an amino acid side chain; a protected amino acid side chain or a peptide chain; and X3is an amino protecting group or one or more amino acids linked by amide bonds where the terminal residue bears an amino protecting group for use in said process.

专利号:US-7145017-B2
优先权日:2002-08-05
标题 :Preparation of Aztreonam
发明人：GYOLLAI VIKTOR; MESZAROS SOS ERZSEBET; SZABO CSABA; SINGER CLAUDE; SALYI SZABOLCS
权利人:TEVA GYOGYSZERGYAR ZARTKOERUEN
摘要:The invention relates to a process for the synthesis of Aztreonam. Specifically, the process entails hydrolyzing [3S-[3α(Z),4β]]-3-[[(2-amino-4-thiazolyl)[(1-t-butoxycarbonyl-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid (t-Bu Aztreonam) to form Aztreonam.

专利号:US-2016326157-A1
优先权日:2014-01-06
标 题:Monobactams and methods of their synthesis and use
发明人：MYERS ANDREW G; Seiple lan Bass; SUSSMAN ROBIN JUDITH
权利人:HARVARD COLLEGE
摘要:Described herein are monobactam antibiotics of Formula (I), (I′), (II), and (II′), along with methods and intermediates for preparing these compounds. Pharmaceutical compositions and methods of treating infectious diseases using the monobactams are also provided.

专利号:CN-105315227-A
优先权日:2014-07-28
标 题:Synthesis of Ceftazidime Intermediate

专利号:CN-106520857-B
优先权日:2016-08-25
标题 :A kind of method for enzymatic synthesis of aztreonam

专利号:WO-2015103583-A1
优先权日:2014-01-06
标 题 :Monobactams and methods of their synthesis and use