专利号:US-8207337-B2 优先权日:2007-01-29 标 题:Reagent for organic synthesis reaction containing organic triol borate salt 发明人:MIYAURA NORIO; YAMAMOTO YASUNORI 权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD 摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).
参考标题:Ruthenium-Catalysed Multicomponent Synthesis Of The 1,3-Dienyl-6-Oxy Polyketide Motif 作者:Barry M. Trost,James J. Cregg,Christoph Hohn,Wen-Ju Bai,Guoting Zhang,Jacob S. Tracy |发布日期:2020.7 摘要:Operation And Can Be Used To Generate Chiral Products. The Successful Development Of This Methodology Relies On The Remarkable Efficiency Of The Ruthenium-Catalysed Alkene-Alkyne Coupling Reaction Between Readily Available Vinyl Boronic Acids And Alkynes To Provide Unsymmetrical 3-Boryl-1,4-Diene Reagents. In The Presence Of Carbonyl Compounds, These Reagents Undergo Highly Diastereoselective Allylations To