CAS: 768-70-7; 3-Ethynylanisole

上下游产品

3-(3-甲氧基苯基)-2-丙炔-1-醇 3-(3-Methoxyphenyl)Prop-2-Yn-1-Ol 27913-19-5
(3-甲氧基苯基乙炔)三甲基硅烷 3-(Trimethylsilylethynyl)Anisole 40230-92-0
3-(3-Methoxyphenyl)Propiolic Acid 7621-89-8
3-甲氧基苯甲醛 3-Methoxy-Benzaldehyde 591-31-1

📜间溴苯甲醚置于bis-Triphenylphosphine-Palladium(II) Chloride,Copper(L) Iodide,Potassium Carbonate,三乙胺体系中,用 四氢呋喃,甲醇 作为反应溶剂,化学反应 34.0H,反应生成 3-乙炔基苯甲醚
参考文献:高选择性且无添加剂的 Pd(Oac)2/cpp 催化炔烃的氢氨基羰基化
标题:高选择性且无添加剂的 Pd(Oac)2/cpp 催化炔烃的氢氨基羰基化
摘要:在此,报道了使用 Pd 通过炔烃与各种胺底物(如芳香胺,脂肪胺,固体胺源如 Nh 4 Hco 3,甚至强碱性哌啶)的氢氨基羰基化反应合成支链 α,β-不饱和酰胺. (Oac) 2 /混合n-杂环卡宾-膦-膦(Cpp)催化体系.该反应具有无添加剂,底物范围广,选择性高(b/l > 99 : 1)和优异的产率的特点.机理研究表明该反应通过氢化钯途径发生的. Cpp采用卡宾-膦配位模式的杂化二齿配体构象,其中一个磷原子保持外部可接近,可能在催化循环过程中充当稳定辅助剂.
DOI:10.1039/d4Ob00644E

专利信息

专利号:US-10829792-B2
优先权日:2017-03-21
标 题 :Biocatalytic synthesis of strained carbocycles
发明人：CHEN KAI; HUANG XIONGYI; KAN S B JENNIFER
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods include combining an alkyne and a carbene precursor in the presence of a heme protein, e.g., a cytochrome P450, under conditions sufficient to form the strained carbocycle. Reaction mixtures for producing strained carbocycles are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming cyclopropenes, bicyclobutanes, and related products.

专利号:US-8835658-B2
优先权日:2012-12-28
标 题:Asymmetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities
发明人：CHAN ALBERT SUN-CHI; FAN BAOMIN; WANG JUN; LIN CHENGYUAN; HUANG CHAO; YANG QINGJING; XU JIANBIN; BIAN ZHAOXIANG; LU AIPING; HU JUN
权利人:UNIV HONG KONG BAPTIST; UNIV YUNNAN NATIONALITIES
摘要:The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.

专利号:US-7402703-B2
优先权日:2005-06-08
标 题:Stereoselective synthesis of (E)-vinylboronic esters via a Zr mediated hydroboration of alkynes
发明人：WANG YANONG DANIEL
权利人:WYETH CORP
摘要:There is herein provided a process for Zr-mediated hydroboration of alkynes which offers (E)-vinylboronic esters in high yield with stereoselectivity and regioselectivity.

专利号:US-2006281943-A1
优先权日:2005-06-08
标题 :Stereoselective synthesis of (E)-vinylboronic esters via a Zr mediated hydroboration of alkynes

专利号:WO-2006132896-A2
优先权日:2005-06-08
标题:Stereoselective synthesis of (e)-vinylboronic esters via a zr mediated hydroboration of alkynes

专利号:US-2014187801-A1
优先权日:2012-12-28
标题:Asymetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities