专利号:US-3998951-A 优先权日:1974-03-13 标 题 :Substituted 2-arylquinazolines as fungicides 发明人:HARNISH WAYNE NELSON; RAMSEY ARTHUR ALBERT 权利人:FMC CORP 摘要:Fungicidal compositions based on substituted 2-arylquinazolines exhibit antifungal activity particularly against rusts and mildews. The synthesis of new compounds is described and the utility of antifungal compositions is exemplified.
专利号:US-5258386-A 优先权日:1991-06-05 标 题 :(+)-3-substituted-N alkylmorphinans, synthesis and use as anticonvulsant and neuroprotective agents 发明人:NEWMAN AMY H; TORTELLA FRANK C 权利人:US ARMY 摘要:It has been discovered that certain (+)-3-substituted-N-alkylmorphinans areffective anticonvulsant and neuroprotective agents. Novel compounds having these biological properties are presented in a method of use for preventing, treating or controlling convulsions in mammals having a need for such treatment. The compounds do not lead to dependency, have low toxicity, and provide effective anticonvulsant or neuroprotective treatment with little or no behavioral detriment to the recipient. A number of pharmacological formulations and methods of administering compounds of the invention are suitable for anticonvulsive or neuroprotective treatments.
专利号:US-4370501-A 优先权日:1981-10-05 标题 :Synthesis of bis(aminophenyl) compounds 发明人:LAU KREISLER S Y 权利人:HUGHES AIRCRAFT CO 摘要:A simplified process for converting bis-phenols to dianilines is disclosed. Selected catalytic complexes are used to cause a nucleophilic displacement reaction between a bis-phenol and a quinazoline to occur thereby yielding a bis-quinazoline that may be subsequently converted into a bis-quinazolinone and hydrolyzed to form the desired dianiline.
专利号:CN-108358794-A 优先权日:2018-02-02 标题:A new method for the synthesis of 2,2-bis(4-aminophenyl)hexafluoropropane
专利号:EP-1370552-B1 优先权日:2001-03-23 标题:Rho-kinase inhibitors 发明人:NAGARATHNAM DHANAPALAN; WANG CHUNGUANG 权利人:BAYER PHARMACEUTICALS CORP 摘要:Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
专利号:CN-108358794-B 优先权日:2018-02-02 标题 :Synthesis method of 2, 2-bis (4-aminophenyl) hexafluoropropane