CAS: 56563-37-2; But-2-Yn-1-Yl 4-Methylbenzenesulfonate

上下游产品

CAS号764-01-2 2-丁炔-1-醇 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号104-15-4 对甲苯磺酸 | CAS号105643-77-4 1-azidobut-2-yne | CAS号4626-58-8 苄基-2-丁炔胺 | CAS号41282-40-0 but-2-yn-1-amine

📜2-丁炔-1-醇,对甲苯磺酸置于氢氧化钾体系中,用 乙醚 作为反应溶剂,化学反应 1.5H,以89%的收率获得产物对甲苯磺酸 2-丁炔酯
参考文献:分子内芳香族烷基化,第 15 届手套.4-甲基-5,6,7,8-四氢-5-喹啉酮的合成
标题:分子内芳香族烷基化,第 15 届手套.4-甲基-5,6,7,8-四氢-5-喹啉酮的合成
摘要:与文献相反,甲基乙烯基酮(1)和烯胺3得到2-甲基喹啉酮4,而不是标题中提到的4-甲基异构体5.这是烯胺11第一次通过热环化或kmno4氧化5,6,7,8-四氢来匹定(7)合成.前体11可从二氢间苯二酚(17)和丁炔胺15获得,其根据改进的文献规定制备.-标题化合物 5 的结构经化学和光谱确定.
DOI:10.1002/ardp.19853181003

专利信息

专利号:US-11542269-B2
优先权日:2018-01-03
标 题:Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof
发明人：CHOI HYEONG-WOOK; FANG FRANCIS G
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods utilizing Prins reaction in the preparation of compounds that may be useful as intermediates in the synthesis of halichondrin macrolides and analogs thereof. The invention also provides compounds that may be useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.

专利号:EP-3737673-A1
优先权日:2018-01-03
标 题 :Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof

专利号:US-2023151022-A1
优先权日:2018-01-03
标题 :Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof

专利号:CN-111868044-A
优先权日:2018-01-03
标题 :Prins reaction and compounds useful for the synthesis of halichondrin macrolides and analogs thereof

专利号:WO-2019136145-A1
优先权日:2018-01-03
标 题:Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof

专利号:US-2014012024-A1
优先权日:2011-03-23
标题 :Method for the synthesis of dha