专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:US-2012232031-A1 优先权日:2009-10-19 标 题:Injectable formulations for intra-articular or peri-articular administration 发明人:HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE 权利人:HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE; PANMIRA PHARMACEUTICALS LLC 摘要:Described herein are injectable formulations for intra-articular or peri-articular administration, wherein the formulation is administered to treat joint pain. An injectable formulation for intra-articular or peri-articular administration disclosed herein comprises a therapeutically-effective amount of a leukotriene synthesis inhibitor compound formulated for intra-articular or peri-articular administration.
专利号:CN-110106146-B 优先权日:2019-03-28 标 题 :Use of the compound ketotifen fumarate in promoting the synthesis and secretion of stem cell factors
专利号:CN-110106146-A 优先权日:2019-03-28 标 题 :Use of the compound ketotifen fumarate in promoting the synthesis and secretion of stem cell factors
专利号:CN-118084883-A 优先权日:2024-02-29 标 题 :A kind of ketotifen impurity and its synthesis method
1: Schwarzer G, Bassler D, Mitra A, Ducharme FM, Forster J. Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children. Cochrane Database Syst Rev. 2004;(1):CD001384. Review. Review. Spanish. Review. Erratum in: Drugs 1991 Feb;41(2):192. Review. Review. German. Review. Review. French. Review. Polish. Review. Review. French. Review. Review. Hebrew. Review. Review.
合成参考文献
参考文献:10.1007/s10384-005-0314-9 摘要:Ebihara N, Nishikawa M, Murakami A. Disodium Cromoglycate Inhibits Capsaicin-Induced Eosinophil Infiltration of Conjunctiva Independent of Mast Cells. Japanese Journal of Ophthalmology. 2006 May;50(3):205–10. doi: 10.1007/s10384-005-0314-9.