CAS: 33507-63-0; Substance P

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CAS号74-87-3 氯甲烷 | CAS号4530-20-5 B°C-甘氨酸 | CAS号13139-15-6 B°C-L-亮氨酸 | CAS号2488-15-5 B°C-L-蛋氨酸 | CAS号13734-34-4 B°C-L-苯丙氨酸

📜在 水体系中,化学反应 2.0H,反应生成多肽物质p
参考文献:Homocysteine Thiolactone As Precursor Of Methionine Amide : Application To The Modification Of Peptides Of The Tachykinin Family
标题:Homocysteine Thiolactone As Precursor Of Methionine Amide : Application To The Modification Of Peptides Of The Tachykinin Family
摘要:
Doi:10.1016/s0040-4039(00)89163-7

专利信息

专利号:US-12410140-B2
优先权日:2020-06-19
标题:Method for synthesis of roxadustat and intermediate thereof, and intermediate thereof
发明人：ZHANG YONG; WANG GUO; YANG FEI; LIU FENGWEI; ZHOU CHUNDONG; ZHANG ZITONG
权利人:JUMPCAN SHANGHAI MEDICAL TECH CO LTD
摘要:Disclosed are a method for the synthesis of roxadustat and an intermediate thereof, and an intermediate thereof. In particular, disclosed is a method for the synthesis of compound M1, the method comprising the following steps: carrying out a reaction as shown below between compound SM and compound SM-A under the action of an oxidizing agent. The method of the present invention uses cheap and easily available raw materials, has short reaction steps, produces a high yield, has simple and convenient post-treatment procedures, and is suitable for industrial production.

专利号:US-2024383940-A1
优先权日:2021-03-31
标题 :Synthesis of trinucleotide and tetranucleotide caps for mrna production
发明人：ENDO ATSUSHI
权利人:MODERNA TX INC
摘要:Provided herein are methods of making trinucleotides and tetranucleotides for use as 5′ mRNA caps. The methods utilize a novel “top-downâ€? strategy and provide for synthesis of oligonucleotides with higher yields and increased efficiency compared to traditional methods. A key step of the methods disclosed, herein can also be adapted to utilize a “one-potâ€? approach, resulting in an increase in the yield of the final oligonucleotide product.

专利号:US-2024294464-A1
优先权日:2021-10-27
标题 :Synthesis of restrained complexing agents
发明人：WONG NICHOLAS; GOSSELIN FRANCIS
权利人:GENENTECH INC
摘要:Improved methods of synthesis of a restrained complexing agent are described herein. Compounds, including salts and solvates thereof, and compositions relevant to the improved methods are also described.

专利号:US-6177564-B1
优先权日:1998-09-11
标题:Process for the synthesis of N-benzyl-3-(4-fluorophenyl)-1-4-oxazin-2-one
发明人：NELSON TODD D; BHUPATHY MAHADEVAN
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of the formula:This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.

专利号:US-2008090274-A1
优先权日:2004-12-16
标 题 :Process For The Synthesis Of (S)-1-(3,5-Bis (Trifluoromethyl)-Phenyl-Ethan-1-Ol
发明人：MOORE JEFFREY C; TRUPPO MATTHEW D; POLLARD JENNIFER M; POLLARD DAVID J; STURR MICHAEL G
权利人:MOORE JEFFREY C; TRUPPO MATTHEW D; POLLARD JENNIFER M; POLLARD DAVID J; STURR MICHAEL G
摘要:The present invention is concerned with novel processes for the preparation of (S)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol (CAS # 30071-93-3). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-6403793-B2
优先权日:2000-06-12
标 题 :Intramolecular glycosidation process for the synthesis of (2R, 2-alpha-R, 3a)-2-[1-(3,5- bis (trifluoromethyl) phenyl)ethoxy]-3-(4-fluorophenyl)-1,4-oxazine
发明人：PYE PHILIP J; ROSSEN KAI
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (2R-cis)-2-[[1-[3.5-bis(trifluoromethyl)phenyl]ethenyl]oxy]-3-(4-fluorophenyl)-4-(phenylmethyl) mopholine. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.