CAS: 144104-59-6; (1H-Indol-5-yl)Boronic Acid

相似化合物

269410-24-4 317830-84-5 147621-18-9

上下游产品

CAS号10075-50-0 5-溴吲哚 | CAS号688-74-4 硼酸三丁酯 | CAS号144104-53-0 5-呋喃-3-基-1H-吲哚 | CAS号144104-44-9 5-(4-氟苯基)-1H-吲哚 | CAS号144104-54-1 5-(2-噻吩基)-1H-吲哚 | CAS号144104-51-8 5-pyrimidin-5-y... | CAS号90679-35-9 5-(PYRIDIN-4-YL... | CAS号128373-22-8 5-(2-糠基)-1H-吲哚 | CAS号100846-24-0 5-(三氟甲基)吲哚 | CAS号144104-46-1 5-(4-甲氧基苯基)-1H-吲哚 | CAS号144104-49-4 5-Pyridin-3-yl-... | CAS号117908-10-8 5-(pyridin-2-yl...

5-溴吲哚置于甲醇,四次甲氨基乙硼烷,Chloro(2-Dicyclohexylphosphino-2',4',6'-Triisopropyl-1,1'-Biphenyl)[2-(2'-Amino-1,1'-Biphenyl)]Palladium(II),Potassium Acetate,2-二环己基磷-2,4,6-三异丙基联苯体系中,化学反应 6.08H,反应生成5-吲哚硼酸
参考文献:钯催化芳基和杂芳基卤化物使用四(二甲氨基)二硼硼化:一步更环保
标题:钯催化芳基和杂芳基卤化物使用四(二甲氨基)二硼硼化:一步更环保
摘要:报道了钯催化芳基和杂芳基卤化物与新型硼酸化剂四(二甲氨基)二硼 [(Me 2 N) 2 B-b(Nme 2 ) 2 ] 的硼化反应.该方法是对先前报道的利用双硼酸 (Bba) 的方法的补充,因为某些底物在一组优化的反应条件下比另一组表现更好.由于四(二甲氨基)二硼是 Bba 和双(频哪醇)二硼(b 2 Pin 2)的合成前体,因此新方法代表了当前硼化方法的原子经济性和效率更高的方法.
Doi:10.1021/ol302124J

专利信息

专利号:US-2024239768-A1
优先权日:2021-04-27
标题 :Method for preparing xanthine oxidase inhibitor
发明人：RYU IN AE; LEE JU YOUNG; YOON JOO YONG; LEE SEOK JU; PARK AH BYEOL; KIM KI DAE; JEONG HUI RAK
权利人:LG CHEMICAL LTD
摘要:The present invention relates to a novel preparation method that can be advantageously utilized for the synthesis of a xanthine oxidase inhibitor of Chemical Formula 1.

专利号:US-2012077802-A1
优先权日:2009-06-10
标题 :Histamine h3 inverse agonists and antagonists and methods of use thereof
发明人：CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN
权利人:CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are spiro-cyclic compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as, e.g., histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical compositions containing the compounds and their methods of use are also provided herein.

专利号:US-2012172350-A1
优先权日:2009-09-11
标题 :Histamine h3 inverse agonists and antagonists and methods of use thereof
发明人：CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN
权利人:CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as, e.g., histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical compositions containing the compounds and their methods of use are also provided herein.

专利号:US-2024262809-A1
优先权日:2021-04-27
标题:Method for preparing intermediate for synthesis of xanthine oxidase inhibitor

专利号:US-11767302-B2
优先权日:2020-10-01
标题 :Reagents and methods for tetrazine synthesis
发明人：FOX JOSEPH M; LAMBERT WILLIAM; FANG YINZHI; AM ENDE CHRISTOPHER WILLIAM; MAHAPATRA SUBHAM; XIE YIXIN; WANG CHUANQI
权利人:UNIV DELAWARE
摘要:Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine.

专利号:WO-2022231261-A1
优先权日:2021-04-27
标 题:Method for preparing intermediate for synthesis of xanthine oxidase inhibitor