CAS: 13361-64-3; Trimethyl(Prop-2-Yn-1-yl)Silane

该化合物是有机硅化合物,其特点是存在三甲基组和丙酰组的硅原子,该化合物具有终端的烷功能组,有助于其反应,特别是结合反应和作为有机合成的一个构件.硅原子的存在具有独特的特性,例如热稳定性增强,并有可能形成硅氧联系.三甲基-2-丙酰-1-硅通常是一种无色液体,有独特的气味,在有机溶剂中可溶解.该化合物的再活动可归因于烷细胞,在各种化学变异中有用,包括交叉相撞反应,并作为更复杂的硅含化合物的前体.在处理该物质时,应注意安全防范措施,因为如果吸入或浸泡,可能会对健康造成危害.

结构式图片

欧盟法规

C&L通报REACH预注册

上下游产品

CAS号75-77-4 三甲基氯硅烷 | CAS号106-96-7 溴代丙炔 | CAS号2295-12-7 环三亚甲基硅烷 | CAS号463-49-0 丙二烯 | CAS号14657-22-8 trimethyl(propa... | CAS号2857-97-8 三甲基溴硅烷 | CAS号111999-85-0 1-trimethylsily... | CAS号111999-87-2 1-(3-trimethyls... | CAS号111999-90-7 tert-butyl-dime... | CAS号491-35-0 4-甲基喹啉 | CAS号21752-80-7 trimethyl(3-tri... | CAS号420-56-4 三甲基氟硅烷 | CAS号31139-07-8 propargyl anion

合成工艺路线路线简述

  • 合成目标产物 Propargyltrimethylsilane 主要起始原料 Chlorotrimethylsilane And Propargyl Bromide
  • (文献来源)合成步骤主要原料 Chlorotrimethylsilane 和 Propargyl Bromide
📜3-溴丙炔 反应生成炔丙基三甲基硅烷
参考文献:Pornet,J.;Damour,D.;Miginiac,L.,Tetrahedron,1986,42,N 7,2017-2024
标题:Pornet,J.;Damour,D.;Miginiac,L.,Tetrahedron,1986,42,N 7,2017-2024

海关参考信息

专利信息


专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人:LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-2025026768-A1
优先权日:2023-06-30
标题:Method for the synthesis of axially chiral organoboron compounds
发明人:PING YIFAN; CHE CHI-MING
权利人:LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:A highly efficient and atroposelective Rh-catalyzed [2+2+2] cycloaddition for the synthesis of axially chiral aryboron compounds is developed. The reactions of diynes and alkynylborons smoothly occur in an atom-economical manner, affording a variety of C—B atropisomers in excellent yields and enantioselectivities. The protocol features mild conditions, broad substrate scope, and good functional tolerance. The obtained C—B atropisomers show powerful synthetic applications in terms of producing novel chiral phosphine ligands.

专利号:US-2007260076-A1
优先权日:2003-12-05
标 题:Practical, Cost-Effective Synthesis of Ubiquinones
发明人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
权利人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人:LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:WO-9902264-A1
优先权日:1997-07-11
标题:Membrane and method for synthesis of hydrogen peroxide
发明人:MCINTYRE JAMES A; SANDERS EDGAR S JR; MAHONEY ROBERT D; WEBB STEVEN P; MURCHISON CRAIG B; HAYES DAVID A
权利人:DOW CHEMICAL CO; MCINTYRE JAMES A; SANDERS EDGAR S JR; MAHONEY ROBERT D; WEBB STEVEN P; MURCHISON CRAIG B; HAYES DAVID A
摘要:This invention is a membrane which is useful for the synthesis of hydrogen peroxide from hydrogen and oxygen. The membrane has a hydrogen contact side and an oxygen contact side and comprises a porous hydrophobic catalyst layer facing the oxygen contact side and a gas flux control layer facing the hydrogen contact side. The gas flux control layer is positioned between the hydrogen contact side and the porous hydrophobic catalyst layer such that the flux of hydrogen may be controllably delivered to the porous hydrophobic catalyst layer. The membrane and method may be used to controllably synthesize hydrogen peroxide directly from hydrogen and oxygen without the use of organic solvents or complex equipment for ionic and electrical transport.

专利号:US-2025304580-A1
优先权日:2021-11-09
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人:HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Wang, K. K., Science of Synthesis, (2008) 44, 268.
摘要:Negishi, E.; Wang, G., Science of Synthesis, (2010) 47, 978.
摘要:Gandon, V.; Thorimbert, S.; Malacria, M., Science of Synthesis, (2009) 46, 173.
摘要:Okamoto, K.; Ohe, K., Science of Synthesis Knowledge Updates, (2020) 1, 88.
摘要:Weibel, J.-M.; Blanc, A.; Pale, P., Science of Synthesis Knowledge Updates, (2018) 1, 15.
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