CAS: 101396-91-2; (S)-3-Chloro-2-Hydroxy-N,N,N-Trimethylpropan-1-Aminium Chloride

上下游产品

N-(3-chloro-2-hydroxypropyl)trimethylammonium chloride D-(+)-3-formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid (2R)-3-chloro-1,2-propanediol trimethylamine hydr°Chloride (S)-N-(3-chloro-2-hydroxypropyl)-N,N,N-trimethylammonium chloride (R)-N-(3-chloro-2-hydroxypropyl)-N,N,N-trimethylammonium chloride L-carnitine O-acetyl-L-carnitine hydr°Chloride

📜(R)-(-)-3-氯-1,2-丙二醇置于氯化亚砜,三甲胺体系中,用 N-甲基乙酰胺 用作溶剂,化学反应生成(S)-(-)-(3-氯-2-羟丙基)三甲基氯化铵
参考文献:Process For Preparing 3-Halogeno-2-Hydroxypropyltrimethylammonium Halide
标题:Process For Preparing 3-Halogeno-2-Hydroxypropyltrimethylammonium Halide

专利信息

专利号:US-4814506-A
优先权日:1986-08-26
标题:Process for preparing 3 halogeno-2-hydroxypropyltrimethylammonium halide
发明人：KATAYAMA KAZUHIKO; HAMAGUCHI SHIGEKI; KOGAME YOSHIKAZU; OHASHI TAKEHISA; WATANABE KIYOSHI
权利人:KANEGAFUCHI CHEMICAL IND
摘要:A process for preparing 3-halogeno-2-hydroxy-propyltrimethylammonium halide or especially one having the (S)-configuration, which comprises reacting 2,3-dihydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is obtained by reacting (R)-3-halogeno-1,2-propanediol with trimethylamine, with a halogenating reagent. According to the present invention, 3-halogeno-2-hydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is a useful intermediate for the synthesis of carnitine or especially (l)-carnitine, can be obtained economically, efficiently and easily.