CAS: 79-83-4; (+)-(R)-3-(2,4-Dihydroxy-3,3-Dimethylbutanamido)Propanoic Acid

该化合物是CHNOS, 与-alain 相关联, 具有一种泛太酸味.该化合物的特征是白色到黄晶状色的外观, 具有合金质, 意味着它可以吸收环境中的湿气. 泛太酸在正常条件下稳定, 但在暴露于高温或极低pH水平时可以降解. 它存在于各种食物中, 包括肉类, 全粒子, 豆类和蔬菜, 使人类饮食中广泛供应. 泛太尼酸的缺乏性是罕见的, 但可导致疲劳, 易腐性和消化问题等症状.

结构式图片

相似化合物

16485-10-2 81-13-0 867-81-2

上下游产品

CAS号599-04-2 D-(-)-泛酰内酯 | CAS号924-73-2 3-氨基丙酸乙酯 | CAS号107-95-9 β-丙氨酸 | CAS号27778-35-4 (R)-2,4-Dihydro... | CAS号867-81-2 泛酸钠 | CAS号1112-33-0 泛醇杂质B | CAS号81-13-0 D-泛醇 | CAS号85-61-0 辅酶A | CAS号599-04-2 D-(-)-泛酰内酯 | CAS号107-95-9 β-丙氨酸 | CAS号67755-97-9 Butanal, 2-hydr... | CAS号124-38-9 二氧化碳 | CAS号138148-35-3 泛硫乙胺

合成工艺路线路线简述

  • 合成目标产物 D-Pantothenic Acid 主要起始原料 Calcium D-Pantothenate
  • (文献来源)合成步骤主要原料 Calcium D-Pantothenate
D-泛醇置于barium Permanganate,硫酸体系中,化学反应生成 D-泛酸
参考文献:Us2377814
标题:Us2377814

海关参考信息

专利信息


专利号:WO-2012017400-A1
优先权日:2010-08-03
标 题 :Synthesis of acyl-pantetheine derivatives and the use thereof in the synthesis of acyl-coenzyme a derivatives
发明人:VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
权利人:UNIV NORTHWEST; VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
摘要:The present invention relates to a novel synthesis method for acyl-pantetheine derivatives. The present invention further relates to the use of said synthesized acyl-pantetheine derivatives as a starting material in the enzymatic synthesis of acyl-coenzyme A derivatives. According to a first aspect thereof, the present invention provides a method for the synthesis of acyl-pantetheine derivatives, the method including the steps of: a) providing a source of pantetheine; b) providing a source of acyl ester; and c) contacting the source of pantetheine with the source of acyl ester to form the corresponding acyl-pantetheine derivative, having the general formula (I), wherein R is an acyl group.The present invention also provides a method for the synthesis of acyl-coenzyme A derivatives as well as the use of a source of pantetheine and a source of acyl ester in the preparation steps of these two methods.

专利号:US-2007088174-A1
优先权日:2005-10-19
标 题 :Synthesis of phenoxyacetic acid derivatives
发明人:WINTER ERIC; REICHEL CARSTEN; GUTHEIL DIETER
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to an improved process for the preparation of substituted 2-(4-carbonylmethoxy-optionally 2,5-disubstituted-phenyl)-acetaldehydes, in particular 2-(4-alkoxycarbonylmethoxy-optionally 2,5-disubstituted-phenyl)-acetaldehydes and their use in the synthesis of optionally substituted 2-[4-[2-[[-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-amino]ethyl]-optionally 2,5-disubstituted-phenoxy]acetic acid derivatives or the salts thereof, which may be used as pharmaceutically active substances.

专利号:US-2023091651-A1
优先权日:2021-09-20
标 题:Dietary supplement and method for synthesis of same
发明人:WYNN JASON R
权利人:StrongCell LLC
摘要:A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided that includes at least partially microencapsulated nicotinamide having nicotinamide blended with water. A supplement component, such as collagen, coenzyme Q10, vitamins, and minerals, is provided. A mixed component, which is a liquid, is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is subjected to a fill production process.

专利号:US-2009247781-A1
优先权日:2004-10-26
标 题:Synthesis of phenoxyacetic acid derivatives
发明人:WINTER ERIC; REICHEL CARSTEN; GUTHEIL DIETER
权利人:KISSEI PHARMACEUTICAL
摘要:The present invention relates to an improved process for the preparation of substituted 2-(4-carbonylmethoxy-optionally 2,5-disubstituted-phenyl-acetaldehydes, in particular 2-(4-alkoxycarbonylmethoxy-optionally 2,5-disubstituted-phenyl)-acetaldehydes and their use in the synthesis of optionally substituted 2-[4-[2-[[-2-hydroxy-2-(4-hydroxyphenyl)- 1 -methylethyl]-amino]ethyl]-optionally 2,5-disubstituted-phenoxy]acetic acid derivatives or the salts thereof, which may be used as pharmaceutically active substances.

专利号:US-2006211083-A1
优先权日:2005-01-21
标题:Products and processes for in vitro synthesis of biomolecules
发明人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.

专利号:US-2023089537-A1
优先权日:2021-09-20
标题:Dietary supplement and method for synthesis of same
发明人:WYNN JASON R
权利人:StrongCell LLC
摘要:A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided which includes NADH from about 0.1% to about 0.5% blended with water from about 40% to about 84% both by weight of the dietary supplement. A supplement component from about 9% to about 99% by weight of the dietary supplement is also provided. The supplement component may include collagen in about 2% to about 10%, vitamins in about 0.00001% to about 3%, and minerals in about 0.000002% to about 0.5% all by weight of the dietary supplement. A mixed component is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is a liquid at ambient conditions having a pH of less than 4.0. The mixed component is subjected to a cold fill production process.
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主要参考文献

[参考文献]: M Sato, Et Al. Pantothenic Acid Decreases Valproic Acid-Induced Neural Tube Defects In Mice (I). Teratology. 1995 Sep;52(3):143-8.
[参考文献]: Shuai Chen, Et Al. Metabolomic Analysis Of The Toxic Effect Of Chronic Exposure Of Cadmium On Rat Urine. Environ Sci Pollut Res Int. 2018 Feb;25(4):3765-3774.

合成参考文献


参考文献:10.1055/s-0028-1109764
摘要:Lammersdorf K, Weissbach A, Meyer CH. [Glued eyelids by cyanoacrylate glue (superglue)]. Klin Monbl Augenheilkd. 2010 Feb;227(2):149–50. doi: 10.1055/s-0028-1109764.
参考文献:10.3390/md9061056
摘要:Lordan S, Ross RP, Stanton C. Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases. Mar Drugs. 2011;9(6):1056–100.
参考文献:10.1042/bj20110326
摘要:Said HM. Intestinal absorption of water-soluble vitamins in health and disease. Biochem J. 2011 Aug 01;437(3):357–72.
参考文献:10.2174/138945011798829384
摘要:Prabhu P, Patravale V. Novel targets for malaria therapy. Curr Drug Targets. 2011 Dec;12(14):2129–43. doi: 10.2174/138945011798829384.
参考文献:10.1016/j.tvjl.2011.06.026
摘要:Galler A, Tran JL, Krammer-Lukas S, Höller U, Thalhammer JG, Zentek J, Willmann M. Blood vitamin levels in dogs with chronic kidney disease. The Veterinary Journal. 2012 May;192(2):226–31. doi: 10.1016/j.tvjl.2011.06.026.
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