专利号:US-6509484-B2 优先权日:1993-02-05 标 题:Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereof 发明人:SWINDELL CHARLES S; KRAUSS NANCY 权利人:NAPRO BIOTHERAPEUTICS INC 摘要:The present invention relates to chemical compounds that are useful in the production of taxanes. The chemical compounds according to the present invention have a generalized formula: n wherein R 1 is + NH 3 X − where X is deprotonated organic acid such as deprotonated trifluoroacetic acid, and wherein R 2 may be acetyl or hydrogen, and P 1 may be hydrogen or a hydroxyl protecting group, such as benzyloxymethyl.
专利号:US-6072060-A 优先权日:1993-02-05 标题:Synthesis of taxol, taxol analogs and their intermediates with variable A-ring side chain structures and compositions thereof
专利号:EP-0682660-B1 优先权日:1993-02-05 标 题:Synthesis of taxol, analogs and intermediates with variable a-ring side chains
专利号:WO-9418186-A1 优先权日:1993-02-05 标题 :Synthesis of taxol, analogs and intermediates with variable a-ring side chains
专利号:EP-0682660-A1 优先权日:1993-02-05 标 题 :Synthesis of taxol, analogs and intermediates with variable a-ring side chains
专利号:US-5770745-A 优先权日:1993-02-05 标 题:Synthesis of taxol, taxol analogs and their intermediates with variable A-ring side chain structures and compositions thereof