CAS: 602-85-7; Lysergol

上下游产品

Lysergen elym°Clavine sodium butanolate butan-1-olO-α-Phenylbutyryl-lysergol O-3-Chlorbenzoyl-lysergol O-3-Methoxybenzoyl-lysergol-hydr°Chlorid O-3,4,5-Trimethoxybenzoyl-lysergol-hydr°Chlorid

Lysergen置于sodium Hydroxide,9-Borabicyclo[3.3.1]Nonane Dimer,双氧水体系中,化学反应生成 麦角醇
参考文献:Conversion Of Agroclavine To Lysergol
标题:Conversion Of Agroclavine To Lysergol
摘要:The Conversion Of Agroclavine (1) To Lysergol (4) Has Been Achieved In Three Steps Utilising The Dehydration Of Setoclavine (2) To Lysergene (3).
DOI:10.1080/00397919208019288

专利信息

专利号:US-3929796-A
优先权日:1974-08-02
标 题:Synthesis of penniclavine and elymoclavine
发明人：KORNFELD EDMUND C; BACH NICHOLAS J
权利人:LILLY CO ELI
摘要:Synthesis of penniclavine and of elymoclavine, intermediates useful therein, and novel compounds producible therefrom.

专利号:US-3968112-A
优先权日:1974-08-02
标 题:Synthesis of penniclavine and elymoclavine
发明人：KORNFELD EDMUND C; BACH NICHOLAS J
权利人:LILLY CO ELI
摘要:Synthesis of penniclavine and of elymoclavine, intermediates useful therein, and novel compounds producible therefrom.

专利号:US-4908449-A
优先权日:1985-07-11
标 题 :Process for preparing N-methyl derivatives of lysergol and 10α-methoxylumilysergol
发明人：GERVAIS CHRISTIAN
权利人:RHONE POULENC SANTE
摘要:A process for preparing 1-methyllysergol or 10 alpha -methoxy-1-methyllumilysergol, which comprises adding a base, which is an alkali metal hydride or alcoholate, to a solution of lyergol or 10 alpha -methoxylumilysergol in a polar aprotic solvent in such a way that the molecular ratio between the base and the lysergol or 10 alpha -methoxylumilysergol remains less than 0.5:1, and then adding a methylating agent which is methyl iodide, methyl sulphate or trimethylsulphonium iodide. 1-methyllysergol and 10 alpha -methoxy-1-methyllysergol are useful intermediates in the synthesis of pharmacological compounds.

专利号:US-9657030-B2
优先权日:2010-06-11
标 题 :Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
发明人：GIGUERE JOSHUA ROBERT; MCCARTHY KEITH EDWARD; REISCH HELGE ALFRED; SANDOVAL SERGIO; STYMIEST JAKE LARRY
权利人:RHODES TECH
摘要:The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

专利号:US-4082753-A
优先权日:1976-02-17
标题:Penniclavine acetonide
发明人：KORNFELD EDMUND C; BACH NICHOLAS J
权利人:LILLY CO ELI
摘要:Synthesis of penniclavine and of elymoclavine, intermediates useful therein, and novel compounds producible therefrom.

专利号:US-4054567-A
优先权日:1975-08-11
标 题:6-Methyl-8β-hydroxymethyl-8-γ-substituted-9-ergolene compounds
发明人：KORNFELD EDMUND C; BACH NICHOLAS J
权利人:LILLY CO ELI
摘要:Synthesis of penniclavine and of elymoclavine, intermediates useful therein, and novel compounds producible therefrom.