CAS: 55576-66-4; (S)-1,1'-(((2,4,6-Trihydroxy-5-(2-Methylbutanoyl)-1,3-Phenylene)Bis(Methylene))Bis(2,4-Dihydroxy-6-Methoxy-5-Methyl-3,1-Phenylene))Bis(Butan-1-One)

上下游产品

2-methyl-1-(2,4,6-trihydroxyphenyl)-1-butanone 1-4,6-dihydroxy-2-methoxy-3-methylphenylbutan-1-one 2,4,6-trihydroxytoluene 1-[3-methyl-2,4,6-trihydroxyphenyl]-1-butanone

专利信息

专利号:US-2025162973-A1
优先权日:2022-02-22
标题:Methods of synthesis and uses of agrimol compounds
发明人：CHE CHI MING; FU ZHIWEN; LEUNG YIU CHUNG GULICE
权利人:VERSITECH LTD; LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:Synthetic agrimol B and derivatives thereof (“compoundsâ€?) that have anticancer properties are disclosed. Methods for synthesizing the compounds with an overall yield ≥7% are disclosed. Pharmaceutical formulations in forms suitable for the delivery of the compounds to a subject in need thereof are disclosed. Methods of using the compounds for treating a cancer, reducing a cancer, or treating or ameliorating one or more symptoms associated with a cancer, such as non-small-cell lung cancer, in a subject are also disclosed. The methods include (i) administering to the subject the pharmaceutical formulation containing one or more compounds, for one or more times. The compounds can selectively kill cancer cells and/or cancer stem cells over noncancerous cells by inducing mitochondria dysfunction and/or inhibiting ER to Golgi trafficking in the cancer cells and/or cancer stem cells.

专利号:WO-2023160543-A1
优先权日:2022-02-22
标 题 :Methods of synthesis and uses of agrimol compounds

专利号:WO-2024126769-A1
优先权日:2022-12-15
标题 :Process for preparing alpha,beta-unsaturated carbonyl compound
发明人：BONOMO LUCIA; JACOBY DENIS; FONTENY FABIEN; KELLER FABRICE
权利人:FIRMENICH & CIE
摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a process for the oxidation of an allylic alcohol into an alpha,beta-unsaturated carbonyl compound in a presence of zirconium catalyst and a hydrogen acceptor.

专利号:WO-2023160543-A9
优先权日:2022-02-22
标题 :Methods of synthesis and uses of agrimol compounds