CAS: 500-98-1; 2-(2-Phenylacetamido)Acetic Acid

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500-98-1 28116-23-6 1189920-31-7

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CAS号56-40-6 甘氨酸 | CAS号103-80-0 苯乙酰氯 | CAS号23776-85-4 PHENYL-ACETIC A... | CAS号28268-03-3 N-Carboxymethyl... | CAS号6000-44-8 甘氨酸钠 | CAS号101-41-7 苯乙酸甲酯 | CAS号103-82-2 苯乙酸 | CAS号1078-60-0 2-benzyl-4H-1,3... | CAS号103-82-2 苯乙酸 | CAS号56-40-6 甘氨酸 | CAS号4838-35-1 (2-苯基乙酰基)甘氨酸乙酯 | CAS号188663-05-0 4-(N,N-二甲基氨基亚甲基... | CAS号881-90-3 2-甲基-4-(苯基亚甲基)噁... | CAS号13140-77-7 N-phenylacetyl-... | CAS号1212-44-8 2-benzyl-4-(met... | CAS号68662-93-1 2-benzyl-4-benz... | CAS号4252-32-8 N-formyl-2-phen...

📜Tert-Butyl (2-Phenylacetyl)Glycinate置于三氟乙酸体系中,化学反应 0.5H,反应生成 苯乙酰甘氨酸
参考文献:The Use Of Cellulose (Chromatography Paper) As A Cheap,Versatile And Non-Covalent Support For Organic Molecules During Multi-Step Synthesis
标题:The Use Of Cellulose (Chromatography Paper) As A Cheap,Versatile And Non-Covalent Support For Organic Molecules During Multi-Step Synthesis
摘要:纤维素色谱纸提供了一种新颖的非共价支持,用于多维阵列的合成和原位纯化.
DOI:10.1039/b208083D

专利信息

专利号:US-5268271-A
优先权日:1989-12-12
标题 :Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin G acylase
发明人：GUISAN SEIJAS JOSE M; FERNANDEZ LAFUENTE ROBERTO; ALVARO CAMPOS GREGORIO; BLANCO MARTIN ROSA M; MOLINA ROSELL CRISTINA
权利人:CONSEJO SUPERIOR INVESTIGACION
摘要:Synthesis of semi-synthetic monobactamic or β-Lactamic antibiotics by using derivatives stabilized by various methods of penicillin G acylase from various microbial sources according to a thermodynamically controlled strategy in monophase water/cosolvent organic apolar systems, wherein the concentration of the cosolvent varies between 30% and 90%, the temperature between -10° C. and 50° C., the pH between 4.5 and 8.5, with concentrations of the antibiotic nucleus between 0.5 an 875 mM and acyl donor between 0.2 mM and 1M, with a relationship antibiotic ring/activated or free acyl donor, using a buffer between 0 and 1M. Application to the pharmaceutical industry.

专利号:WO-2014150173-A1
优先权日:2013-03-15
标 题 :Method for identifying inhibitors of protein-protein interaction
发明人：WAGNER GERHARD; HAGNER PATRICK RYAN; ARTHANARI HARIBABU; GELEV VLADIMIR M; RODRIGUEZ RICARD A; FAHMY AMR
权利人:HARVARD COLLEGE
摘要:A method of using NMR and combinatorial synthesis to identify compounds that bind to a target protein is provided. Embodiments of the present disclosure are directed to methods of making compounds including one or more fragments that bind to a target protein. The target protein may be one which is known to have a binding partner. The compound including one or more fragments that bind to the target protein may be an inhibitor of the binding or other interaction between the target protein and binding partner. According to one aspect, binding fragments are attached to a polypeptide backbone in a conformation which allows binding of the fragments to the target protein.

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:GB-589406-A
优先权日:1945-03-21
标题:Improvements in and relating to the synthesis of oxazolones

专利号:US-2006211603-A1
优先权日:2004-08-18
标 题:Ramoplanin derivatives possessing antibacterial activity
发明人：RAJU BORE G; CIABATTI ROMEO; MAFFIOLI SONIA I; SINGH UPINDER; ROMANO GABRIELLA; MICHELUCCI ELENA; TISENI PAOLO S; CANDIANI GIANPAOLO; KIM BUM; O'DOWD HARDWIN
权利人:VICURON PHARM INC
摘要:Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

专利号:US-2024209353-A1
优先权日:2021-04-08
标 题 :Nadk2 inhibition in cancer and fibrotic disorders
发明人：THOMPSON CRAIG B; SCHWOERER SIMON; ZHU JIAJUN
权利人:MEMORIAL SLOAN KETTERING CANCER CENTER; MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES; SLOAN KETTERING INST CANCER RES
摘要:Aspects of the disclosure provide methods for inhibiting cell proliferation and protein synthesis utilizing an antagonist of nicotinamide adenine dinucleotide kinase 2 (NADK2). In some aspects, these methods are used to treat a disease such as cancer or a disorder such as a fibrotic disorder. Further provided herein are compositions comprising a nutrient-deficient cell culture medium and an antagonist of NADK2.