CAS: 4091-75-2; 16α-Chloro-3-Methoxy-Estra-1,3,5(10)-Trien-17-One

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    合成工艺路线路线简述

      📜3-Methoxy-17-Acetoxy-1,3,5(10),16-Estratetraene置于氯体系中,化学反应生成 16-Alpha-氯-3-甲氧基雌甾-1,3,5(10)-三烯-17-酮
      参考文献:16α-Chloro-And 16α-Iodoestrone Methyl Ether,New And Potent Lipid-Shifting Agents
      标题:16α-Chloro-And 16α-Iodoestrone Methyl Ether,New And Potent Lipid-Shifting Agents
      摘要:
      DOI:10.1021/ja01540A070

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      专利信息


      专利号:US-10925977-B2
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
      发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
      权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
      摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

      专利号:KR-101513003-B1
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy compositions and applications

      专利号:US-10814013-B2
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      专利号:AU-2007308022-A2
      优先权日:2006-10-05
      标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      专利号:AU-2007308022-A1
      优先权日:2006-10-05
      标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

      专利号:US-2008107598-A1
      优先权日:2006-10-05
      标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

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      ✅ COA系统入驻 | 共享模式

      合成参考文献


      摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
      摘要:SANGIULO F, CALVANO V. [Clinical observations on the hypocholesterolemic and anti-arteriosclerotic action of 16 alpha-chloroestrone methylether]. Rass Int Clin Ter. 1960 Nov 30;40():1244–51.
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