CAS: 37661-08-8; Bacampicillin Hydrochloride

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CAS号40966-78-7 2-(R)-2-phenyl-... | CAS号69-53-4 氨苄西林

📜Magnesium Sulfate,氨苄西林,1-溴乙基乙基碳酸酯置于盐酸,碳酸氢钠体系中,用 乙酸丁酯,水,乙酸乙酯,丙酮 作为反应溶剂,化学反应生成 盐酸巴氨西林
参考文献:Preparation Of 1'-Ethoxycarbonyl-Oxyethyl Esters Of Penicillins
标题:Preparation Of 1'-Ethoxycarbonyl-Oxyethyl Esters Of Penicillins
摘要:制备青霉素1'-乙氧羰氧乙酯的过程,其中化合物的结构式为##str1##其中a是苯基,苯氧基或4-羟基苯基,B是氢,氨基或保护的氨基,Z是氢或从碱金属,三(较低烷基)氨基和四(较低烷基)氨基组中选择的阳离子,与1-溴乙基乙基碳酸酯在有机溶剂中反应,当b是保护的氨基时,保护基被去除以产生一次氨基.还提供了结构式为##str2##其中ph是苯基,R是ch.Sub.3--或c.Sub.2H.Sub.5--的新化合物.

专利信息

专利号:US-9693999-B2
优先权日:2011-01-26
标题:Small molecule RNase inhibitors and methods of use
发明人：DUNMAN PAUL M; OLSON PATRICK D; CHILDERS WAYNE
权利人:UNIV ROCHESTER; UNIV NEBRASKA; Temple University—Of the Commonwealth System of Higher Education
摘要:Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.

专利号:US-2007203079-A1
优先权日:2005-11-21
标题:Methods of using small molecule compounds for neuroprotection
发明人：CALDWELL GUY A; CALDWELL KIM A; CAO SONGSONG
权利人:CALDWELL GUY A; CALDWELL KIM A; CAO SONGSONG
摘要:Methods are provided for preventing neurodegeneration and neuronal loss by administering compositions comprising small molecule compounds with the effect of preventing neurodegeneration and neuronal loss. In one aspect of the invention, the methods and compositions are also useful for treating neurodegenerative diseases. Small molecule compounds provide an important treatment option because of their stability, ease of use in both manufacture and formulation, ease of administration, and patient compliance. The small molecule compound compositions of the present invention may include topoisomerase II inhibitors, bacterial transpeptidase inhibitors, calcium channel antagonists, cyclooxygenase inhibitors, folic acid synthesis inhibitors, or sodium channel blockers and functional analogues thereof that have an effect on neurodegeneration. The compositions of the present invention may be administered prophylactically before the onset of clinical symptoms or after clinical symptoms of a neurodegenerative disease have manifested.

专利号:WO-2009056955-A1
优先权日:2007-10-30
标题 :Amine-bearing phospholipids (abps), their synthesis and use
发明人：ZUMBUEHL ANDREAS
权利人:UNIV BASEL; ZUMBUEHL ANDREAS
摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.

专利号:US-9868747-B2
优先权日:2014-02-18
标题:Marinopyrrole derivatives and methods of making and using same
发明人：LI RONGSHI; SEBTI SAID; LIU YAN; QIN YONG; SONG HAO; CHENG CHUNWEI
权利人:H LEE MOFFITT CANCER CT & RES; CHONGQING ZEIN PHARMACEUTICAL CO LTD
摘要:Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

专利号:US-9493497-B2
优先权日:2012-04-26
标题:Carbamate glycolipid and use thereof
发明人：TASHIRO TAKUYA; MORI KENJI; SHIOZAKI MASAO; TANIGUCHI MASARU; WATARAI HIROSHI
权利人:RIKEN
摘要:The invention provides a compound effective as an antitumor active agent or vaccine adjuvant and an intermediate useful for the synthesis of the compound, as well as production methods thereof, and a medicament containing the novel compound. The compound is a carbamate glycolipid represented by the formula (I) n nwherein each symbol is as defined herein. The invention also provides a dendritic cell pulsed with the glycolipid.

专利号:US-9907753-B2
优先权日:2010-03-19
标 题 :Lipid vesicle compositions and methods of use
发明人：IRVINE DARRELL J; MOON JAEHYUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.