CAS: 2057-49-0; 4-(3-Phenylpropyl)Pyridine

该化合物是一种有机化合物,其特点是在4点用三苯丙基丙基组替代了环,在4点上,该化合物一般呈现黄色至褐色液体形式,由于有苯基组的存在,具有独特的芳香味,在乙醇和乙醚等有机溶剂中可溶解,但在水中溶解性有限,该化合物对包括药用化学和有机合成在内的各个领域都感兴趣,因为它具有潜在的生物活动和应用,是合成更复杂的分子的建筑块,其结构允许各种相互作用,成为药理学和材料科学研究的候选物.安全数据表明,与许多有机化合物一样,应当谨慎地处理它,使用适当的安全措施避免吸入或皮肤接触.

结构式图片

相似化合物

82106-08-9 865075-16-7 1184078-51-0

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上下游产品

picoline styrene 3-Oxo-1-phenyl-3-pyridin-4-ylpropan 1-phenyl-2-bromoethane 4-(3-phenylpropyl)pyridine-N-oxide 1-methyl-4-(3-phenylpropyl)-1,2,3,6-tetrahydropyridine 1Benzyl-4-(3-phenylpropyl)-1,2,3,6-tetrahydropyridine 4,4'-di-(3-phenylpropyl)-2,2'-bipyridyl

合成工艺路线路线简述

    烯丙苯置于potassium Fluoride,Palladium Diacetate,1,2-双(二环己基磷基)-乙烷体系中,用 甲苯 用作溶剂,化学反应 42.0H,反应生成4-(3-苯基丙基)吡啶
    参考文献:钯催化的酯基烷基交叉偶联中的可切换选择性
    标题:钯催化的酯基烷基交叉偶联中的可切换选择性
    摘要:公开了pd催化的苯基酯和烷基硼烷的交叉偶联.通过交换催化剂,可以选择性地接近两种反应模式.使用pd-Nhc系统,可以通过激活c(酰基)-O键进行的suzuki-Miyaura反应,以高收率制备烷基酮.使用pd-二氯乙烯催化剂可使烷基化的芳烃通过co挤出的修饰途径合成.讨论了这种分歧偶联策略的应用以及可切换选择性的起源.
    Doi:10.1021/acs.Orglett.8B01646

    海关参考信息

    专利信息


    专利号:US-4732945-A
    优先权日:1986-10-15
    标题 :Synthesis by reacting oxirane resin with carboxyl compounds
    发明人:DAMMANN LAURENCE G
    权利人:ASHLAND OIL INC
    摘要:Disclosed is a new partial capping synthesis wherein resinous mixtures containing controlled amounts of phenolic hydroxyl and/or mercapto functionality, and aliphatic hydroxyl functionality are synthesized. Such synthesis comprises providing one or more resins which in total contain aliphatic primary and/or secondary hydroxyl functionality and oxirane functionality. A single resin or blend of resins may provide the requisite functionality. The one or more resins then are reacted with a carboxyl-functional capping agent bearing phenolic hydroxyl functionality and/or mercapto functionality. This reaction is conducted under reaction conditions and for a time such that the carboxyl functionality of the capping agent selectively reacts with the oxirane functionality of the one or more resins to produce a resinous product containing aliphatic hydroxyl functionality and containing phenolic hydroxyl functionality and/or mercapto functionality.

    专利号:US-4826617-A
    优先权日:1986-10-15
    标题:Selective resin synthesis and dual functional resins made thereby
    发明人:DAMMANN LAURENCE G
    权利人:ASHLAND OIL INC
    摘要:Disclosed is a new partial capping synthesis wherein resinous mixtures containing controlled amounts of phenolic hydroxyl and/or mercapto functionality, and aliphatic hydroxyl functionality are synthesized. Such synthesis comprises providing one or more resins which in total contain aliphatic primary and/or secondary hydroxyl functionality and oxirane functionality. A single resin or blend of resins may provide the requisite functionality. The one or more resins then are reacted with a carboxyl-functional capping agent bearing phenolic hydroxyl functionality and/or mercapto functionality. This reaction is conducted under reaction conditions and for a time such that the carboxyl functionality of the capping agent selectively reacts with the oxirane functionality of the one or more resins to produce a resinous product containing aliphatic hydroxyl functionality and containing phenolic hydroxyl functionality and/or mercapto functionality.

    专利号:WO-2025097667-A1
    优先权日:2023-11-08
    标题:Mixture, composition, and use thereof in electronic device
    发明人:PAN JUNYOU; ZHANG HAO
    权利人:ZHEJIANG BRILLIANT OPTOELECTRONIC TECH CO LTD
    摘要:Disclosed is a mixture, comprising: at least one first compound H1 represented by formula (I) and at least one second compound H2, the second compound H2 being preferentially selected from bicarbazole derivatives. An organic compound or mixture of the present invention, when used as a phosphorescent light-emitting host material, can improve the efficiency of devices and the service life of devices. In particular, an organic mixture can strike a good balance between electron holes and electron transport speed, and achieve low efficiency roll-off and a long service life of OLED devices at high brightness. Moreover, the material provided by the invention has a relatively simple synthesis process and is low cost, so that the material has huge application potential and application range. The invention further relates to a composition and an organic electronic device, and in particular relates to an organic electroluminescent device.
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    主要参考文献

    [参考文献]: Frank Marken, Et Al. Ion Transfer Processes At 4-(3-Phenylpropyl)-Pyridine/aqueous Electrolyte/electrode Triple Phase Boundary Systems Supported By Graphite And By Mesoporous Tio2. Faraday Discuss. 2005:129:219-29; Discussion 275-89.
    [参考文献]: Stuart M Macdonald, Et Al. Probing Carboxylate Gibbs Transfer Energies Via Liquid|liquid Transfer At Triple Phase Boundary Electrodes: Ion-Transfer Voltammetry Versus Cosmo-Rs Predictions. Phys Chem Chem Phys. 2008 Jul 14;10(26):3925-33.

    合成参考文献


    摘要:Nakao, Y., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 428.
    摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129.
    摘要:Shehzad, A.; Vu, H. D.; Devi, K.; Bissinger, B. R. G.; Wiesenfeldt, M. P., Science of Synthesis: Dearomatizations, (2026) .
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