CAS: 17795-27-6; (Allylsulfinyl)Alanine

该化合物是一个氨酸衍生物,其特征是配有丙烯基磺酰胺的成份,附着于丙烯基磺酸碳的甲型丙烯酸;该化合物具有硫基功能组,有助于其独特的反应和潜在的生物活动;该丙烯基组引入不饱和,允许各种化学变异和相互作用;作为氨基酸衍生物,保留氨基酸的基本结构,包括一个矿组,一个碳本酸组,以及影响其特性的侧链;该硫基组的存在可能提高其在极地溶剂中的溶性,影响其与生物系统的互动,有可能使其在制药和生物化学研究中感兴趣;此外,该化合物的立体化学和功能组可以在其反应和与其他分子的互动方面发挥重要作用,这可能与药物设计或代谢途径有关.

结构式图片

MSDS等安全信息

    上下游产品

    S-allyl cysteine S-propenyl-L-cysteine (S)-3-(allylthio)-2-aminopropanoic acid S-allyl-N-formyl-DL-cysteineS-allyl-N-formyl-DL-cysteine (2R)-2-(acetylamino)-3-(prop-2-en-1-ylsulfanyl)propanoic acid S-allyl cysteine (+/-)-S-propyl-L-cysteine sulfoxide allicin

    合成工艺路线路线简述

      📜Dl-S-烯丙基半胱氨酸置于双氧水体系中,化学反应 0.05H,以66.5%的收率获得蒜氨酸
      参考文献:一种蒜氨酸的制备方法
      标题:一种蒜氨酸的制备方法
      摘要:本发明公开了一种蒜氨酸的制备方法.该制备方法包括以下步骤:在微反应器中,将如式2所示的脱氧蒜氨酸和氧化剂在溶剂中进行氧化反应,得到如式1所示的蒜氨酸,所述氧化剂与所述如式2所示的脱氧蒜氨酸的摩尔比值为0.9~1.2.本发明所述蒜氨酸的制备方法中原料转化率高,最终产品纯度高,比旋度高,反应时间短,副反应少,且操作简单,后处理简单,具有较好的应用市场.

      海关参考信息

      专利信息


      专利号:US-6362009-B1
      优先权日:1997-11-21
      标 题 :Solid phase synthesis of heterocycles
      发明人:MUNOZ BENITO; CHEN CHIXU
      权利人:MERCK & CO INC
      摘要:Methods for solid phase and combinatorial synthesis using a resin activation/capture approach are provided. In particular, methods for the production of dihydropyridones, N-acyidihydropyridones, tetrahydropyridones, pyridines, aminopyridines, N-acyltetrahydropyridines and tetrahydropyridines compounds and libraries containing such compounds are provided. Methods for screening the libraries and compounds and pharmaceutical compositions containing compounds prepared by the methods are provided.

      专利号:US-2014357576-A1
      优先权日:2013-05-31
      标题:Methods for enhancement of muscle protein synthesis
      发明人:BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
      权利人:NESTEC SA
      摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

      专利号:WO-2014009759-A3
      优先权日:2012-07-13
      标题 :Improvements in or relating to allium extracts
      发明人:BENNETT N; RAMSEY EDWARD DALHOUSIE
      权利人:LEPTREX LTD
      摘要:The present invention relates to improvements in or relating to Allium extracts. In particular, it relates to improvements in or relating to extending the therapeutic half- life or duration of Allium extracts. The invention also relates to the synthesis of certain thiosulfinate compounds, especially to the synthesis of methyl allyl thiosulfinate and allyl methyl thiosulfinate, in particular from either methiin or alliin alone or a mixture of both. The invention further relates to the synthesis of methyl allyl thiosulfinate, allyl methyl thiosulfinate, allicin, and methyl methyl thiosulfinate in a mixture with varying molar or mass ratios depending on the reaction conditions, in particular from either methiin or alliin alone or a mixture of both. A high yielding, optimized synthesis of allicin starts from alliin, whereas methyl methyl thiosulfinate is advantageously obtained from methiin. Also provided is a kit comprising methiin in a first container and/or alliin in a second container and an allinase source, in particular garlic powder in a third container. Finally, the invention provides a method of preparing a mixture of methyl allyl thiosulfinate, allyl methyl thiosulfinate, allyl allyl thiosulfinate (allicin) and methyl methyl thiosulfinate from methiin and pieces of an Allium species.

      专利号:WO-2015040533-A1
      优先权日:2013-09-19
      标题:Methods for enhancing muscle protein synthesis during energy deficit
      发明人:BAILEY DAVID MARK; ZALTAS ERIC SCOTT; STELLINGWERFF TRENT; MOORE DANIEL RYAN; HAWLEY JOHN ALAN; BURKE LOUISE MARY
      权利人:PREMIER NUTRITION CORP
      摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis during periods of negative energy balance, or energy deficit. The methods include administering to an individual suffering from energy deficit a composition comprising protein in an amount from about 15 g to about 30 g during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof. The methods also include administering to an individual suffering from energy deficit a composition comprising protein during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof, wherein the protein is administered in a dose that is higher than doses typically recommended for individuals experiencing energy balance.

      专利号:US-2014294788-A1
      优先权日:2013-03-26
      标 题 :Methods for enhancing muscle protein synthesis following concurrent training
      发明人:BAILEY DAVID MARK; ZALTAS ERIC SCOTT; MOORE DANIEL RYAN; STELLINGWERFF TRENT
      权利人:NESTEC SA
      摘要:The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.

      专利号:US-7094943-B2
      优先权日:1998-04-27
      标 题 :Solution phase biopolymer synthesis
      发明人:KOESTER HUBERT; WOERL RALF
      权利人:KOESTER HUBERT; WOERL RALF
      摘要:Multifunctional liquid phase carriers (LPCs) and methods of using LPCs for the preparation of biopolymers are provided. The LPCs are highly symmetrical compounds that possess more than two points of attachment for biopolymer synthesis. The LPCs have the formula Sp(X 1 ) n , where Sp is a highly symmetrical moiety such that all X 1 groups are equivalent. X 1 is a functional group that is suitable for biopolymer synthesis, including OH, SH, NH 2 , COOH and the like. Biopolymers that may be produced using the methods provided include oligonucleotides, peptides, protein nucleic acids (PNAs) and oligosaccharides. Analogs of the biopolymers may also be prepared using the methods.

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      合成参考文献


      摘要:Yoshimoto, F. K.; Li, Q., Science of Synthesis Knowledge Updates, (2012) 1, 241.
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