CAS: 120964-45-6; (1S,2R,5R)-5-(4-Amino-1H-Imidazo[4,5-C]Pyridin-1-yl)-3-(Hydroxymethyl)Cyclopent-3-Ene-1,2-Diol Hydrochloride

上下游产品

-4,5-O-isopropylidene-2-cyclopenten-1-ol methanesulfonate(1S,4R,5S)-(-)-3-(benzyloxy)methyl-4,5-O-isopropylidene-2-cyclopenten-1-ol methanesulfonate 4-chloro-1H-imidazo[4,5-c]pyridine -4-chloroimidazopyridine(-)-1-(1R,4R,5S)-3-(Hydroxymethyl)-4,5-dihydroxy-2-cyclopenten-1-yl-4-chloroimidazo4,5-cpyridine -4-chloroimidazopyridine(-)-1-(1R,4R,5S)-3-(Benzyloxymethyl)-4,5-O-isopropylidene-2-cyclopenten-1-yl-4-chloroimidazo4,5-cpyridine

📜1-[(3Ar,6R,6As)-2,3A-Dimethyl-4-(Phenylmethoxymethyl)-6,6A-Dihydrocyclopenta[d][1,3]Dioxol-6-Yl]-4-Chloroimidazo[4,5-C]Pyridine 反应生成3-去氮腺嘌呤a
参考文献:Tseng,Christopher K. H.;Marquez,Victor E.;Fuller,Richard W.;Goldstein,+,J. Med. Chem.,32,(1989) N,C. 1442-1446
标题:Tseng,Christopher K. H.;Marquez,Victor E.;Fuller,Richard W.;Goldstein,+,J. Med. Chem.,32,(1989) N,C. 1442-1446

专利信息

专利号:US-2009270431-A1
优先权日:2005-10-19
标 题 :Cyclopentenol Nucleoside Compounds Intermediates for their Synthesis and Methods of Treating Viral Infections
发明人：CHU DAVID C K; CHO JONG HYUN; KIM HYO-JOONG
权利人:UNIV GEORGIA RES FOUND
摘要:The present invention relates to compounds according to the structure (I), Where B is formula (Ia), formula (Ib) or formula (Ic); A is H, OR 2 or halogen (F, Cl, Br, I, preferably F or Br, more preferably F); A′ is H, OR2 or halogen (F, Cl, Br, I, preferably F or Br, more preferably F); A″ is H or OR 1 , with the proviso that when A′ is OR, A is H; and when A is OR 2 , A′ is H; X is C—R 3 or N; Y is C—R 3 or N; preferably X or Y is N and X and Y are not both simultaneously N; R 3 is H or C 1 -C 3 alkyl; D is H or NHR 2 ; E is absent or H; G is O or NHR 2 ; J is N or C—R 4 ; K is N or C—H; R 4 is H, halogen (F, Cl, Br, I), CN, —C(â•?O)NH 2 , NH 2 , NO 2 , —Câ•?C—H (cis or trans) or —C≡C—H; R a is H or CH 3 ; Each R 1 is independently H, an acyl group, a C 1 -C 20 alkyl or ether group, a phosphate, diphosphate, triphosphate, phosphodiester group; Each R 2 is independently H, an acyl group, a C 1 -C 20 alkyl or ether group;and Pharmaceutically acceptable salts, solvates or polymorphs thereof.

专利号:WO-2007047793-A2
优先权日:2005-10-19
标 题 :Cyclopentenol nucleoside compounds, intermediates for their synthesis and methods of treating viral infections