CAS: 109-12-6; Pyrimidin-2-Amine

相似化合物

931-61-3 22715-27-1 50840-23-8

上下游产品

CAS号4595-60-2 2-溴嘧啶 | CAS号542-78-9 丙二醛 | CAS号3993-78-0 2-氨基-4-氯嘧啶 | CAS号102-52-3 1,1,3,3-四甲氧基丙烷 | CAS号50-01-1 盐酸胍 | CAS号1722-12-9 2-氯嘧啶 | CAS号603151-65-1 1,1,3-trimethox... | CAS号603151-66-2 1,1,3-trimethox... | CAS号768388-22-3 1,3,3-trimethox... | CAS号56-05-3 2-氨基-4,6-二氯嘧啶 | CAS号104691-51-2 4-咪唑并[1,2-a]吡啶-2-苯甲腈 | CAS号52687-97-5 2-氯-N-2-嘧啶基乙酰胺 | CAS号57892-71-4 2-(氯甲基)咪唑并[1,2-a]嘧啶 | CAS号57892-76-9 2-氯甲基咪唑并[1,2-a]吡啶盐酸盐 | CAS号5428-89-7 2-氨基-5-氯嘧啶 | CAS号78641-64-2 3,5-dinitro-1-(... | CAS号100-01-6 对硝基苯胺 | CAS号147094-02-8 N-pyrimidin-2-y... | CAS号21025-62-7 2-(嘧啶-2-氨基亚甲基)-...

丙二醛 以97%的收率获得1,3,5-三嗪-2,4,6-三胺,N,N'''-1,2-乙二基二[n-[3-[[4,6-二[丁基(2,2,6,6-四甲基-4-哌啶基)氨基]-1,3,5-三嗪-2-基]氨基]丙基]-N,N''-二丁基-N,N''-二(2,2,6,6-四甲基-4-哌啶基)-
参考文献:Manufacture Of Derivatives Of Malondialdehyde
标题:Manufacture Of Derivatives Of Malondialdehyde
摘要:通式为##equ1##的化合物可以在合成反应中替代丙二醛,该化合物可以通过一步反应从二甲基甲酰胺,光气和烷基乙烯醚中得到.

专利信息

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-9994567-B2
优先权日:2015-05-22
标 题:Synthesis of heterocyclic compounds
发明人：IBRAHIM PRABHA N; LIN JACK; SPEVAK WAYNE; ZHANG JIAZHONG
权利人:PLEXXIKON INC
摘要:Provided herein are intermediates and processes useful for facile synthesis of compounds of formula (I): n nor a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Q, P 1 and P 2 are as defined in this disclosure.

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:US-8334381-B2
优先权日:2006-11-16
标题 :Process for the preparation of intermediates useful in the synthesis of imatinib
发明人：FALCHI ALESSANDRO; GRENDELE ENNIO; MOTTERLE RICCARDO; STIVANELLO MARIANO
权利人:FALCHI ALESSANDRO; GRENDELE ENNIO; MOTTERLE RICCARDO; STIVANELLO MARIANO; ITALIANA SINT SPA
摘要:It is the object of the present invention a process for the preparation of 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine and analogues thereof, intermediates useful for the synthesis of Imatinib, or 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide.

专利号:US-4266058-A
优先权日:1979-07-04
标 题:Synthesis of 2-isopropylamino-pyrimidine
发明人：DEMOSTHENE CLAUDE G; ASPISI CHRISTIAN R
权利人:SOC D ETUDES PROD CHIMIQUE
摘要:The present invention provides a process for the synthesis of 2-isopropylamino-pyrimidine by aminolysis of 2-methylsulphonyl-pyrimidine using isopropylamine. The aminolysis is effected, according to the present invention, by refluxing isopropylamine and 2-methylsulphonyl-pyrimidine in the absence of a solvent. Using this technique, the 2-isopropylamino-pyrimidine has been obtained in a substantially quantitative yield.

专利号:US-8492390-B2
优先权日:2002-05-08
标题 :Synthesis of locked nucleic acid derivatives
发明人：DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER; SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α- L -oxy-LNA, amino-LNA, α- L -amino-LNA, thio-LNA, α- L -thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues.