CAS: 10401-11-3; 3-Ethynylphenol

相似化合物

768-70-7 918826-08-1 3052427-14-9

上下游产品

(1S,2R)-3-Trimethylsilanylethynyl-cyclohexa-3,5-diene-1,2-diol 3-(3-hydroxyphenyl)-2-propynoic acid 3-Iodophenol bromobenzene 3-Hydroxyacetophenone m-(tert-butyldimethylsiloxy)phenylacetylene 1-(2-methylthiophenyl)-2-(3-hydroxyphenyl)acetylene 1-(3-methylthiophenyl)-2-(3-hydroxyphenyl)acetylene

3-碘苯酚置于甲醇,Bis-Triphenylphosphine-Palladium(II) Chloride,Copper(L) Iodide,二甲胺,Potassium Hydroxide体系中,用 四氢呋喃 用作溶剂,化学反应 34.0H,反应生成3-羟基苯基乙炔
参考文献:Btk抑制剂及其用途
标题:Btk抑制剂及其用途
摘要:本发明公开了btk抑制剂及其用途,具体地,本发明提供一类杂芳化合物或其立体异构体,几何异构体,互变异构体,消旋体,氮氧化物,水合物,溶剂化物,代谢产物,药学上可接受的盐或前药,以及包含本发明化合物的药物组合物;本发明还公开了本发明化合物或其药物组合物在制备药物中的用途,该药物用于治疗自体免疫疾病,炎性疾病或增殖性疾病.

专利信息

专利号:US-10829792-B2
优先权日:2017-03-21
标 题 :Biocatalytic synthesis of strained carbocycles
发明人：CHEN KAI; HUANG XIONGYI; KAN S B JENNIFER
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods include combining an alkyne and a carbene precursor in the presence of a heme protein, e.g., a cytochrome P450, under conditions sufficient to form the strained carbocycle. Reaction mixtures for producing strained carbocycles are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming cyclopropenes, bicyclobutanes, and related products.

专利号:US-9744252-B2
优先权日:2011-08-17
标 题:Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi
发明人：BERGER MARKUS; KRUGER MARTIN; LOHRKE JESSICA; REINHARDT MICHAEL; SIEBENEICHER HOLGER
权利人:PIRAMAL IMAGING SA
摘要:The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein IIb/IIIa antagonists for imaging of thrombi.

专利号:US-4131748-A
优先权日:1977-06-29
标题:P-Terphenylene-dicarboxylic acids and their synthesis
发明人：ARNOLD FRED E; WOLFE JAMES F
权利人:US AIR FORCE
摘要:p-Terphenylene-dicarboxylic acids in which aromatic groups are attached to the middle phenyl group of the terphenylene moiety. The compounds are useful as monomers in the preparation of rod-like, para-ordered aromatic heterocyclic polymers.

专利号:WO-2022006548-A1
优先权日:2020-07-02
标题:Inhibitors of yap/taz-tead oncoproteins, synthesis and use thereof

专利号:EP-2305808-B1
优先权日:2001-06-20
标 题:Templated molecules and methods for using such molecules
发明人：PEDERSEN HENRIK; GOULIAEV ALEX HAAHR; SAMS CHRISTIAN KLARNER; SLØK FRANK ABILGAARD; FRESKGÃ…RD PER-OLA; HOLTMANN ANETTE; OLSEN EVA KAMPMANN; HUSEMOEN GITTE NYSTRUP; FELDING JAKOB; FRANCH THOMAS; THISTED THOMAS; HYLDTOFT LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER
权利人:NUEVOLUTION AS
摘要:The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g . therapeutic activity.

专利号:US-9688980-B2
优先权日:2001-06-20
标 题 :Templated molecules and methods for using such molecules
发明人：PEDERSEN HENRIK; GOULIAEV ALEX HAAHR; FRANCH THOMAS; SAMS CHRISTIAN KLARNER; OLSEN EVA KAMPMANN; SLOK FRANK ABILGAARD; HUSEMOEN GITTE NYSTRUP; FELDING JAKOB; HYLDTOFT LENE; NORREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRODER; THISTED THOMAS; FRESKGARD PER-OLA; HOLTMANN ANETTE
权利人:NUEVOLUTION AS; NUEVOLUTION
摘要:The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.