📜N-Benzyloxycarbonyl-(S)-2-Amino-3-(Dimethylamino)Propanoic Acid置于palladium 10% On Activated Carbon,氢气体系中,用 甲醇 用作溶剂,以96.3 %的收率获得3-(N,N-二甲基氨基)-L-丙氨酸 参考文献: Compounds As Immunomodulators Of Pd-L1 Interactions[fr] Composés à Utiliser En Tant Qu'Immunomodulateurs D'Interactions Pd-L1 标题: Compounds As Immunomodulators Of Pd-L1 Interactions[fr] Composés à Utiliser En Tant Qu'Immunomodulateurs D'Interactions Pd-L1 摘要:Pd-L1 Inhibitors Of Various Compound Formulas,Both Generically And Specifically Are Disclosed. Methods Of Making Such Pd-L1 Inhibitor Compounds Are Disclosed,Both Generically And Specifically. Methods Of Using Such Pd-L1 Inhibitor Compounds Singly Or In Combination With Additional Agents And Compositions Of Such Pd-L1 Inhibitor Compounds For The Treatment Of Cancer And Other Conditions Are Disclosed.
专利号:US-2020354404-A1 优先权日:2019-05-09 标 题 :Peptidomimetic agents, synthesis and uses thereof 发明人:AL-ABED YOUSEF 权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH 摘要:Compounds for use in synthesis of peptidomimetic agents; synthesis of peptidomimetic agents; peptidomimetic diagnostic and therapeutic agents; and uses of the compounds and peptidomimetic agents in drug discovery, diagnosis, prevention and treatment of diseases are described.
专利号:US-2023037284-A9 优先权日:2018-11-30 标题:Combination therapy of peptidomimetic macrocycles 发明人:GUERLAVAIS VINCENT; ANNIS DAVID ALLEN 权利人:AILERON THERAPEUTICS INC 摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-2025084410-A1 优先权日:2015-01-12 标 题:Incorporation of unnatural nucleotides and methods thereof 发明人:PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E 权利人:SYNTHORX INC 摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
专利号:US-2018371021-A1 优先权日:2017-05-11 标 题 :Peptidomimetic macrocycles and uses thereof 发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN 权利人:AILERON THERAPEUTICS INC 摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-10919882-B2 优先权日:2019-05-09 标题:Compounds for use in synthesis of peptidomimetics
专利号:CN-115515937-A 优先权日:2020-05-08 标 题:Dimers for the synthesis of peptidomimetics
参考标题:Asymmetric Synthesis Of β-Substituted α-Amino Acids Via A Chiral Nlii Complex Of Dehydroalanine 作者:Yuri N. Belokon',Ashot S. Sagyan,Silva M. Djamgaryan,Vladimir I. Bakhmutov,Vasili M. Belikov |发布日期:1988.1
合成参考文献
摘要:CRC Handbook of Antibiotic Compounds, Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980, 4(1)(51), 1980 参考文献:10.1186/1471-2180-10-35 摘要:Han X, Dorsey-Oresto A, Malik M, Wang JY, Drlica K, Zhao X, Lu T. Escherichia coli genes that reduce the lethal effects of stress. BMC Microbiol. 2010 Feb 04;10():35.