CAS: 99566-27-5; Neuropeptide Ff
该化合物是一个合成的浸泡物,由氨酸序列组成.这种浸泡物具有苯丙烯(Phe),(Leu),胺(Gln),(Pro)和(Pro),(Arg)的特点,以其沉积终端为特征,可影响其稳定性和溶性.这种物质经常展示具体的生物活动,有可能作为信号分子或在各种生理过程中发挥作用.芳香氨酸,如苯丙烯,可能助长水恐惧性相互作用,而的装载荷侧链可在水环境中增强溶性.这种浸泡物的序列和结构也会影响其与生物目标的相容和相互作用,使其在生物化学,药理学和生物技术等领域引起兴趣.进一步的研究将有必要阐明其具体的生物功能和潜在治疗环境.
- 英文名称Neuropeptide Ff
- 中文名称神经肽-FF
- 其它别名NeuropeptideFF (ox); F8F-amide; L-Phenylalaninamide,L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-; Neuropeptide FF; Neuropeptide FF (human); Neuropeptide FF (mouse); NeuropeptideFF (rat)
- CAS编号99566-27-5
- MFCD编号:MFCD00076704
- 分子式:C54H76N14O10分子量:1081.27
- 产品CID: 2031688
- 产品分类生物化工 → 多肽
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303 may be harmful by ingestion +H313 may be harmful by skin contact +h2413 may be harmful by inhalation
- 防范说明P264 wash thoroughly after treatmentp280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masksp305 if in eyesp351 rinse carefully with water for a few minutesp338 remove contact lenses (if any) and easy to operate, continue rinsingp337 if eye irritation persistsp2393 get medical advice / care
- UN编号NONH for all modes of transport
- 安全声明H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- WGK Germany3
上下游产品
1-(tert-butoxycarbonyl)-L-proline B°C-Gln-OH N-tert-butoxycarbonyl-L-phenylalanineN-tert-butoxycarbonyl-L-phenylalanine B°C-Arg(Tos)-OH合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
2921211000-乙二胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/s1043-6618(05)80017-9
摘要:Attila M, Kurkijarvi U, Kivipelto L, Panula P, Ahtee L. The antiopioid peptide, neuropeptide FF, enhances the effects of acute morphine on the cerebral monoamines in rats. Pharmacol Res. 1995 Nov;32(5):293–8. doi: 10.1016/s1043-6618(05)80017-9.
参考文献:10.1002/cne.10205
摘要:Lu D, Lee K, Horodyski FM, Witten JL. Molecular characterization and cell‐specific expression of a Manduca sexta FLRFamide gene. J of Comparative Neurology. 2002 Apr 04;446(4):377–96. doi: 10.1002/cne.10205.
参考文献:10.1016/s0306-4522(01)00587-5
摘要:Cador M, Marco N, Stinus L, Simonnet G. Interaction between neuropeptide FF and opioids in the ventral tegmental area in the behavioral response to novelty. Neuroscience. 2002;110(2):309–18. doi: 10.1016/s0306-4522(01)00587-5.
参考文献:10.1016/j.peptides.2006.04.002
摘要:Fang Q, Guo J, He F, Peng YL, Chang M, Wang R. In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist. Peptides. 2006 Sep;27(9):2207–13. doi: 10.1016/j.peptides.2006.04.002.
参考文献:10.1016/j.ejphar.2015.10.016
摘要:Pan JX, Wang ZL, Li N, Zhang N, Wang P, Tang HH, Zhang T, Yu HP, Zhang R, Zheng T, Fang Q, Wang R. Effects of neuropeptide FF and related peptides on the antinociceptive activities of VD-hemopressin(α) in naive and cannabinoid-tolerant mice. Eur J Pharmacol. 2015 Nov 15;767():119–25. doi: 10.1016/j.ejphar.2015.10.016.
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