CAS: 78388-61-1; Methyl 1-Amino-1-Cyclopentanecarboxylate

该化合物是一种环戊烷衍生酯,具有氨基和碳箱酸甲酯功能组,使其成为有机合成的多用途中间体,其环戊烷环和双功能性使各种药物,农用化学品和特殊化学品的准备应用得以应用.该化合物的活性允许选择性的修改,如矿物质组的双向结合或进一步衍生.在标准条件下与通用溶剂的兼容性增强了其在多步骤合成途径中的效用.该化合物在药用化学中特别有用,用于建造受限制的松木头,改善代谢稳定性和调整目标分子的物理化学特性.

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60421-23-0 52-52-8 10316-79-7

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上下游产品

CAS号60421-23-0 环亮氨酸甲酯盐酸盐 | CAS号67-56-1 甲醇 | CAS号52-52-8 环亮氨酸 | CAS号699-51-4 1,3-二氮杂螺[4.4]壬烷... | CAS号759442-73-4 2-甲基-1,3-二氮杂螺[4...

合成工艺路线路线简述

  • 合成目标产物 Methyl 1-Amino-1-Cyclopentanecarboxylate 主要起始原料 Cyclopentanone
  • (文献来源)合成步骤主要原料 Cyclopentanone
📜环亮氨酸甲酯盐酸盐置于碳酸氢钠体系中,用 水 作为反应溶剂,化学反应生成 1-氨基-1-环戊烷甲酸甲酯
参考文献:Substituted Imidazolone Derivatives,Preparations And Uses
标题:Substituted Imidazolone Derivatives,Preparations And Uses
摘要:本发明涉及多取代咪唑酮衍生物,包括它们的药物组合物以及在人类和动物健康领域中的治疗用途.本发明还涉及一种制备这些衍生物的方法.

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专利信息


专利号:US-2006167268-A1
优先权日:2002-04-09
标 题:Growth hormone secretagogues
发明人：EVERS BRITTA; GERD RUEHTER; MARTIN DE LA NAVA EVA M; TEBBE MARK J
权利人:ELI LILLY AND COMPANY PATENT D
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:CN-104341450-B
优先权日:2013-08-09
标题 :A kind of synthesis of phosphocreatine derivative and pharmaceutical applications

专利号:US-7396846-B2
优先权日:2002-04-09
标题:Growth hormone secretagogues
发明人：EVERS BRITTA; GERD RUEHTER; MARTIN DE LA NAVA EVA MARIA; TEBBE MARK JOSEPH
权利人:LILLY CO ELI
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:US-7125840-B2
优先权日:2001-10-09
标题:Substituted dipeptides as growth hormone secretagogues
发明人：DODGE JEFFREY ALAN; EVERS BRITTA; JUNGHEIM LOUIS NICKOLAUS; MUEHL BRIAN STEPHEN; RUEHTER GERD; THRASHER KENNETH JEFF
权利人:LILLY CO ELI
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:CN-104341450-A
优先权日:2013-08-09
标 题 :Synthesis and pharmaceutical application of a kind of sulfonamide derivative

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合成参考文献


参考文献:10.1055/s-0033-1339865
摘要:Synthesis of MK-3207. Synfacts. 2013 Oct 18;9(11):1151. doi: 10.1055/s-0033-1339865.
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