CAS: 65032-27-1; Ethynylmagnesium Chloride

该化合物是属于灰色试剂类的有机金属化合物,其特征是存在与一个苯乙烯组(CC)和氯化离子结合的镁原子,该化合物一般在二乙醚或四氢呋喃等有机溶剂中呈现无色至浅黄色溶液;氯化乙烷具有高度反应性,特别是水和水,导致乙炔的释放和氢氧化镁的形成;由于其核循环特性,该化合物通常用于有机合成,形成碳-碳联结,能够制造各种碳-碳联结衍生物;该化合物必须在惰性大气中处理,以防止脱腐化,并通常储存在密封容器中,以保持其反应性;在与该试剂合作时,安全防范是不可或缺的,因为它可能是易燃和腐蚀性的.

结构式图片

欧盟法规

C&L通报

上下游产品

CAS号1112-00-1 ethynyl(trimeth... | CAS号4187-87-5 1-苯基-2-丙炔-1-醇 | CAS号1849-39-4 triethynyl(meth... | CAS号1849-38-3 tetraethynylsilane | CAS号25284-22-4 triethynyl(phen... | CAS号994-89-8 三丁基乙炔基锡 | CAS号6229-00-1 三苯基硅乙炔 | CAS号140391-06-6 triphenyl(4-tri... | CAS号105-31-7 1-己炔-3-醇 | CAS号7383-19-9 1-庚炔-3-醇

合成工艺路线路线简述

    正丁基氯化镁,乙炔 反应生成 乙炔基氯化镁
    参考文献:Holmes,Andrew B.;Sporikou,Chris N.,Org. Synth.,New York Etc.,(1987) C. 61-67
    标题:Holmes,Andrew B.;Sporikou,Chris N.,Org. Synth.,New York Etc.,(1987) C. 61-67

    海关参考信息

    专利信息


    专利号:US-7615169-B2
    优先权日:2004-09-20
    标题 :Method for synthesis of colloidal nanoparticles
    发明人:STROUSE GEOFFREY FIELDING; GERBEC JEFFREY A; MAGANA DONNY
    权利人:UNIV CALIFORNIA
    摘要:A method for synthesis of high quality colloidal nanoparticles using comprises a high heating rate process. Irradiation of single mode, high power, microwave is a particularly well suited technique to realize high quality semiconductor nanoparticles. The use of microwave radiation effectively automates the synthesis, and more importantly, permits the use of a continuous flow microwave reactor for commercial preparation of the high quality colloidal nanoparticles.

    专利号:US-7927516-B2
    优先权日:2004-09-20
    标题 :Method for synthesis of colloidal nanoparticles
    发明人:STROUSE GEOFFREY F; GERBEC JEFFREY A; MAGANA DONNY
    权利人:UNIV CALIFORNIA
    摘要:A method for synthesis of high quality colloidal nanoparticles using comprises a high heating rate process. Irradiation of single mode, high power, microwave is a particularly well suited technique to realize high quality semiconductor nanoparticles. The use of microwave radiation effectively automates the synthesis, and more importantly, permits the use of a continuous flow microwave reactor for commercial preparation of the high quality colloidal nanoparticles.

    专利号:US-12037623-B2
    优先权日:2018-07-09
    标 题 :Enzymatic synthesis of 4′-ethynyl nucleoside analogs
    发明人:HUFFMAN MARK A; FRYSZKOWSKA ANNA; KOLEV JOSHUA N; DEVINE PAUL N; CAMPOS KEVIN R; TRUPPO MATTHEW; NAWRAT CHRISTOPHER C
    权利人:MERCK SHARP & DOHME; MERCK SHARP & DOHME LLC
    摘要:The present invention relates to an enzymatic synthesis of 4′-ethynyl-2′-deoxy nucleosides and analogs thereof, for example EFdA, that eliminates the use of protecting groups on the intermediates, improves the stereoselectivity of glycosylation and reduces the number of process steps needed to make said compounds. It also relates to the novel intermediates employed in the process.

    专利号:US-7074932-B2
    优先权日:1999-06-24
    标题 :Preparation of quinoline-substituted carbonate and carbamate derivatives
    发明人:ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
    权利人:ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
    摘要:The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

    专利号:US-2024301460-A1
    优先权日:2018-07-09
    标题 :Enzymatic synthesis of 4'-ethynyl nucleoside analogs

    专利号:US-2007264834-A1
    优先权日:2004-09-20
    标题:Method for Synthesis of Colloidal Nanoparticles
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    合成参考文献


    摘要:Yanagisawa, A., Science of Synthesis, (2004) 7, 524.
    摘要:Yanagisawa, A., Science of Synthesis, (2004) 7, 523.
    摘要:Frost, C. G.; Le Nôtre, J., Science of Synthesis, (2008) 36, 288.
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