CAS: 3426-08-2; 1-(3,3-Diphenylpropyl)Azepane

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    CAS号111-49-9 环己亚胺 | CAS号530-48-3 1,1-二苯基乙烯 | CAS号201230-82-2 carbon monoxide | CAS号571246-03-2 N-cynnamylhexam... | CAS号71-43-2 苯 | CAS号4392-24-9 肉桂基溴 | CAS号83898-29-7 4-(azepan-1-yl)... | CAS号6763-93-5 六氢-1H-氮杂-1-丙酸乙酯

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      📜溴乙基二苯乙腈置于sodium Amide,Xylene体系中,化学反应生成普罗扎平
      参考文献:Alpha-Alpha-Diphenyl-Gamma-Hexamethyleneiminobutyramide
      标题:Alpha-Alpha-Diphenyl-Gamma-Hexamethyleneiminobutyramide

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      专利信息


      专利号:US-7993390-B2
      优先权日:2002-02-08
      标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
      发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
      权利人:BOSTON SCIENT SCIMED INC
      摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

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      主要参考文献

      参考标题:Benzimidazolin-2-Ylidene N-Heterocyclic Carbene Complexes Of Ruthenium As A Simple Catalyst For The N-Alkylation Of Amines Using Alcohols And Diols
      作者:Siah Pei Shan,Xie Xiaoke,Boopathy Gnanaprakasam,Tuan Thanh Dang,Balamurugan Ramalingam,Han Vinh Huynh,Abdul Majeed Seayad
      摘要:For The Alkylation Of Amines Using Alcohols As Alkylating Agents. Catalysts 1, 2 And 3A Gave Excellent Yields Of Up To 99% For The Alkylation Of Various Amines Using Benzylic And Aliphatic Alcohols At 130 °C For 18 H Under Solventless Conditions. Catalyst 3A Bearing Both Phosphine And Carbene Ligands Gave Excellent Yields Of Up To 98% For The Synthesis Of Heterocyclic Amines By Double Alkylation Of Primary

      合成参考文献


      摘要:Kalck, P.; Urrutigoïty, M., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 466.
      参考文献:10.1016/0731-7085(96)01775-x
      摘要:De Orsi D, Gagliardi L, Tonelli D. High performance liquid chromatographic determination of prozapine in pharmaceutical formulations. Journal of Pharmaceutical and Biomedical Analysis. 1996 Aug;14(11):1635–8. doi: 10.1016/0731-7085(96)01775-x.
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