CAS: 27538-10-9; 2-Ethyl-4-Hydroxy-5-Methylfuran-3(2H)-One

该化合物是化学化合物,以其独特的芳香和口味特性而闻名,被归类为类,经常与甜,果和花料有关,使其在香味和口味行业中具有价值.结构上,Pophanneol具有松果环,有助于其独特的感官特性.该化合物通常存在于各种天然来源,包括某些水果和花卉,合成用于食品和化妆品.Hopolinaneol具有潜在的抗氧化特性,可在各种配方中产生更多好处.它与其他成分的稳定性和兼容性使得它成为产品开发中的多种添加剂.与许多有机化合物一样,安全评估至关重要,在消费品中使用同氟醇时必须遵守管制准则.

结构式图片

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27538-09-6 3658-77-3 114099-96-6

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

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CAS号80037-19-0 3-ethyl-2,2'-di... | CAS号73920-09-9 2,5-dibromohept... | CAS号87-72-9 L-阿拉伯糖 | CAS号56-41-7 L-丙氨酸 | CAS号58-86-6 D-木糖 | CAS号56-40-6 甘氨酸

合成工艺路线路线简述

    📜(2E)-2-Ethylidene-4-Hydroxy-5-Methyl-3(2H)-Furanone置于quinone Oxidoreductase From Fragaria X Ananassa,Strawberry,还原型辅酶ii(Nadph)四钠盐体系中,用 Aq. Buffer 用作溶剂,化学反应 24.0H,反应生成2-乙基-4-羟基-5-甲基-3(2H)-呋喃酮
    参考文献:依赖烟酰胺的烯还原酶作为还原活化烯烃的替代生物催化剂
    标题:依赖烟酰胺的烯还原酶作为还原活化烯烃的替代生物催化剂
    摘要:研发了四种 Nad(P)H 依赖性非黄素烯还原酶通过使用 20 种结构不同的底物以不对称方式还原活化的 C=c 键的能力.与依赖黄素的老黄酶同系物相比,需要更高程度的电子活化,因为使用烯醛和硝基烯烃而不是烯酮和羧酸酯获得了最佳活性.尽管来自 Fragaria X Ananassa(草莓)的 Faeo 及其来自番茄(番茄)的同源物 Sleo 表现出狭窄的底物谱,但来自拟南芥(thale Cress)的孕酮 5β-还原酶(at5β-Str)和白三烯 B4 12-羟基脱氢酶(lt4Dh来自褐家鼠 (Rat) 的 Pgr) 似乎是有希望的候选物,特别是对于开链烯醛,硝基烯烃和 α 的不对称生物还原,β-不饱和γ-丁内酯.竞争性硝基还原和非酶促 Weitz-Scheffer 环氧化在很大程度上受到抑制.
    Doi:10.1002/ejoc.201200776

    海关参考信息

    专利信息


    专利号:US-2014228554-A1
    优先权日:2011-03-18
    标 题:Synthesis of new fucose-containing carbohydrate derivatives
    发明人:CHAMPION ELISE; DEKANY GYULA; HEDEROS MARKUS; AGOSTON KAROLY
    权利人:GLYCOM AS; GLYCOM AS
    摘要:A method for the synthesis of a fucooligosaccharide glycosides by reacting a fucosyl donor with H-A-R 1 or a salt thereof, wherein A and R 1 are as defined herein, under the catalysis of an enzyme capable of transferring fucose is provided. The fucooligosaccharid glycoside compounds, or derivatives thereof, their use in the manufacture of human milk oligosaccharides, and a method of manufacture of human milk oligosaccharides, are also provided.

    专利号:EP-2686330-A1
    优先权日:2011-03-18
    标题 :Synthesis of new fucose-containing carbohydrate derivatives

    专利号:WO-2012127410-A1
    优先权日:2011-03-18
    标 题 :Synthesis of new fucose-containing carbohydrate derivatives

    专利号:CN-110343681-B
    优先权日:2019-08-01
    标题:Glycosyltransferase mutant proteins for the synthesis of furanones and their derivatives glucosides

    专利号:US-11371068-B2
    优先权日:2017-12-12
    标 题:Extracellular heme production method using metabolically engineered microorganism
    发明人:LEE SANG YUP; Zhao xin rui; CHOI KYEONG ROK
    权利人:KOREA ADVANCED INST SCI & TECH
    摘要:The present invention relates to a microorganism variant having the ability to extracellularly produce heme, and more particularly to a metabolically engineered microorganism variant having the ability to extracellularly produce heme and a method of producing heme using the same. According to the present invention, heme, an organometallic compound which is increasingly used as a health food or food supplement for the treatment of porphyria , can be extracellularly secreted and produced in high yield using the microorganism variant, but not conventional chemical synthesis or enzymatic synthesis.

    专利号:US-2025091984-A1
    优先权日:2022-04-07
    标题:Fragrance and flavor materials
    发明人:DICKERSON THALIA S; TURESKI ROBERT; BLANDINO MAUREEN
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The present disclosure is directed to the synthesis and application of novel compounds having unique and desired flavor and/or fragrance characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor compounds in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such fragrance or flavor compounds and/or fragrance or flavor compositions.

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    合成参考文献


    摘要:The Good Scents Company Information System
    摘要:Drug and Chemical Toxicology., 3(249), 1980 []
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