CAS: 1988-10-9; 4-Hydroxy Propofol

上下游产品

2,6-diisopropylphenol 2,6-diisopropyl-1,4-benzoquinone 4-Amino-2,6-diisopropylphenol hydr°Chloride 2,6-Diisopropyl-4-nitrophenol 2,6-diisopropyl-4-methoxyphenol 2,6-Di-isopropyl-4-tert.-butoxy-phenol 3,5-diisopropyl-2-methylbenzene-1,4-diol 2,6-diisopropyl-3,5-dimethylbenzene-1,4-diol

📜丙泊酚置于硫酸,双氧水,溶剂黄146体系中,用20.4%的收率获得4-羟基丙泊酚
参考文献:超越dpph:使用荧光抑制自动氧化来预测氧化性细胞死亡抢救.
标题:超越dpph:使用荧光抑制自动氧化来预测氧化性细胞死亡抢救.
摘要:"抗氧化剂活性"是经常被调用的但通常表征不佳的分子性质.有几种测定方法可用于确定抗氧化剂的活性,其中最流行的是基于假定的抗氧化剂还原2,2-二苯基-1-吡啶并肼基的能力.在这里,我们表明该测定的结果与推定的抗氧化剂作为ferroptosis抑制剂(与(磷脂)脂质过氧化有关的氧化性细胞死亡方式)的效力不相关.随后,我们描述了我们的工作,以开发一种方法,该方法可量化假定的抗氧化剂与传播(磷酸)脂质过氧化的(磷酸)脂质过氧化自由基(称为fenix [荧光激活的抑制性自氧化])的反应性.
Doi:10.1016/j.Chembiol.2019.09.007

专利信息

专利号:US-3947473-A
优先权日:1972-12-22
标 题 :Antioxidant chroman compounds
发明人：SCOTT JOHN WILLIAM; PARRISH DAVID RICHARD; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.

专利号:US-4018799-A
优先权日:1973-11-19
标题:Antioxidant chroman compounds
发明人：SCOTT JOHN WILLIAM; PARRISH DAVID RICHARD; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.

专利号:US-4026907-A
优先权日:1973-11-19
标题 :Antioxidant chroman compounds
发明人：SCOTT JOHN WILLIAM; PARRISH DAVID RICHARD; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.

专利号:US-4003919-A
优先权日:1973-11-19
标题:Antioxidant chroman compounds
发明人：SCOTT JOHN WILLIAM; PARRISH DAVID RICHARD; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.