CAS: 1554458-53-5; N-Cyclopropyl-4-(6-(2,3-Difluoro-4-Methoxyphenoxy)-8-((3,3,3-Trifluoropropyl)Amino)Imidazo[1,2-B]Pyridazin-3-yl)-2-Methylbenzamide
- 英文名称N-Cyclopropyl-4-(6-(2,3-Difluoro-4-Methoxyphenoxy)-8-((3,3,3-Trifluoropropyl)Amino)Imidazo[1,2-B]Pyridazin-3-yl)-2-Methylbenzamide
- 中文名称N-环丙基-4-[6-(2,3-二氟-4-甲氧基苯氧基)-8-[(3,3,3-三氟丙基)氨基]咪唑并[1,2-b]哒嗪-3-基]-2-甲基苯甲酰胺
- IUPAC名称N-cyclopropyl-4-(6-(2,3-difluoro-4-methoxyphenoxy)-8-((3,3,3-trifluoropropyl)amino)imidazo[1,2-b]pyridazin-3-yl)-2-methylbenzamide
- 其它别名Benzamide, N-Cyclopropyl-4-[6-(2,3-Difluoro-4-Methoxyphenoxy)-8-[(3,3,3-Trifluoropropyl)Amino]Imidazo[1,2-B]Pyridazin-3-Yl]-2-Methyl-
- CAS编号1554458-53-5
- MFCD编号:MFCD30502614
- FDA UNII编号:M964LB1114
- 分子式:C27H24F5N5O3分子量:561.51
- 产品CID: 770596
- 产品分类Inhibitors/Agonists → Cell Cycle → Mps1 | Inhibitors/Agonists → Cell Cycle → Kinesin
物理性质
合成工艺路线路线简述
海关参考信息
- 2905110000-甲醇
2912110000-甲醛
2912210000-苯甲醛
2903399090-其他无环烃卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Wengner AM, Siemeister G, Koppitz M, Schulze V, Kosemund D, Klar U, Stoeckigt D, Neuhaus R, Lienau P, Bader B, Prechtl S, Raschke M, Frisk AL, von Ahsen O, Michels M, Kreft B, von Nussbaum F, Brands M, Mumberg D, Ziegelbauer K. Novel Mps1 kinase inhibitors with potent anti-tumor activity. Mol Cancer Ther. 2016 Feb 1. pii: molcanther.0500.2015. [Epub ahead of print]
合成参考文献
参考文献:10.1158/1535-7163.mct-15-0500
摘要:Wengner AM, Siemeister G, Koppitz M, Schulze V, Kosemund D, Klar U, Stoeckigt D, Neuhaus R, Lienau P, Bader B, Prechtl S, Raschke M, Frisk AL, von Ahsen O, Michels M, Kreft B, von Nussbaum F, Brands M, Mumberg D, Ziegelbauer K. Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity. Mol Cancer Ther. 2016 Apr;15(4):583–92. doi: 10.1158/1535-7163.mct-15-0500.
参考文献:10.1055/s-0040-1706822
摘要:Taking Two Monopolar Spindle 1 Kinase Inhibitors to Clinical Trials. Synfacts. 2020 Jul 21;16(08):0978. doi: 10.1055/s-0040-1706822.
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