📜二苯甲酰基甲烷置于lithium Aluminium Tetrahydride,乙醚体系中,化学反应生成达泊西汀杂质25 参考文献:Reduction Of Some Enolizable β-Dicarbonyl Compounds To Unsaturated Alcohols By Lithium Aluminum Hydride. Ii. β-Diketones1 标题:Reduction Of Some Enolizable β-Dicarbonyl Compounds To Unsaturated Alcohols By Lithium Aluminum Hydride. Ii. β-Diketones1 摘要: Doi:10.1021/ja01111A034
专利号:CN-105018439-A 优先权日:2015-05-19 标题:A carbonyl reductase and its application in the synthesis of chiral hydroxyl compounds
专利号:DE-602005005645-T2 优先权日:2004-03-18 标题 :STEREOSELECTIVE SYNTHESIS OF VITAMIN D ANALOGUE
专利号:US-6239146-B1 优先权日:1998-06-02 标 题:Neurotrophic difluoroamide agents 发明人:VRUDHULA VIVEKANANDA M; DUBOWCHIK GENE M; DASGUPTA BIRESHWAR; VYAS DOLATRAI M 权利人:BRISTOL MYERS SQUIBB CO 摘要:The present invention relates to the design, synthesis, and the peptidyl-prolyl isomerase (PPIase or rotamase) inhibitory activity of novel alpha,alpha-difluoroacetamido compounds that are neurotrophic agents (i.e. compounds capable of stimulating growth or proliferation of nervous tissue) and that bind to immunophilins such as FKBP12 and inhibit their rotamase activity. This invention also relates to pharmaceutical compositions comprising these compounds.
专利号:US-4845201-A 优先权日:1987-01-22 标题:Process for producing organolanthanides, the resultant compounds and their use 发明人:CHAUVIN YVES; COMMEREUC DOMINIQUE; HUGUES FRANCOIS; OLIVIER HELENE; SAUSSINE LUCIEN 权利人:INST FRANCAIS DU PETROLE 摘要:A process for producing organolanthanides by reaction of a rare-earth metal with an unsaturated compound in an ether medium, the resultant compounds and the use of these compounds in organic synthesis and for catalysis is disclosed. The process is conducted at -80° to +100° C., in the absence of oxygen and any compound having active protons. The resultant compounds are useful as catalysts, e.g., in the hydrogenation of olefins and diolefins and in the polymerization thereof, and are useful as chemical intermediates.
专利号:CN-119243184-A 优先权日:2024-11-22 标题 :Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent
摘要:Thieuleux, C.; Crozet, D., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 2, 325. 摘要:Whittlesey, M. K., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 291. 摘要:Treacy, S. M.; Zhang, X.; Rovis, T., Science of Synthesis, (2021) , 627.