CAS: 109-09-1; 2-Chloropyridine

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CAS号109-04-6 2-溴吡啶 | CAS号2402-95-1 2-氯吡啶-N-氧化物 | CAS号142-08-5 2-羟基吡啶 | CAS号694-59-7 吡啶-N-氧化物 | CAS号77332-76-4 2-氯-3-三甲基甲硅烷基吡啶 | CAS号263698-97-1 2-chloro-6-(tri... | CAS号821773-96-0 (6-chloropyridi... | CAS号2587-00-0 2,6-二氯代吡啶-N-氧化物 | CAS号2127-03-9 2,2'-二硫二吡啶 | CAS号139393-81-0 5-ethyl-6-methy... | CAS号108958-36-7 2-(3-甲氧基苄基)哌啶 | CAS号110225-73-5 3-(2-吡啶)环己酮 | CAS号32111-34-5 4-(2-吡啶基)苯甲腈 | CAS号34803-66-2 1-(2-吡啶基)哌嗪 | CAS号64728-49-0 1,4-二(2-吡啶基)哌嗪 | CAS号381248-04-0 2-氯吡啶-3-硼酸 | CAS号372-48-5 2-氟吡啶 | CAS号20885-12-5 6-氟-2-氯吡啶 | CAS号4282-47-7 2-(4-硝基苯基)吡啶 | CAS号42416-20-6 [2-(Pyridin-2-y...

2-溴吡啶置于co2Cl4(Bis(1H-1,2,3-Triazolo[4,5-B],[4,5-I])Dibenzo[1,4]Dioxin),Potassium Chloride体系中,用 1,4-二氧六环 用作溶剂,以55 %的收率获得2-氯吡啶
参考文献:钴 (III) 卤化物金属-有机框架驱动催化卤素交换
标题:钴 (III) 卤化物金属-有机框架驱动催化卤素交换
摘要:复杂(杂)芳烃系统的选择性卤化是一个关键但具有挑战性的转变,与药物化学,农业和生物医学成像有关.然而,目前的方法受到有毒试剂,昂贵的均相第二排和第三排过渡金属催化剂或较差的底物耐受性的限制.在此,我们证明了含有末端 Co(III) 卤化物位点的多孔金属有机框架 (mof) 代表了一类罕见且通用的非均相催化剂,用于使用简单的金属卤化物盐将氯和氟中心受控地安装到缺电子(异)芳基溴中.机理研究支持这些卤素交换 (halex) 反应通过 Co(III) 位点的氧化还原中性亲核芳香族取代 (snar) 进行.基于 Mof 的 Halex 催化剂是可回收的,可实现绿色卤化,产生最少的废物,并促进 Halex 的连续流动.我们的研究结果代表了使用 Mof 进行 Snar 催化的第一个例子,扩展了这些材料实现的合成转化的词典.
Doi:10.1021/jacs.3C13872

专利信息

专利号:WO-2009018504-A1
优先权日:2007-08-01
标题 :Process for the synthesis of diaminopyridine and related compounds
发明人：RITTER JOACHIM C
权利人:DU PONT; RITTER JOACHIM C
摘要:A process is provided for the synthesis of a diaminopyridine, such as 2,6-diaminopyridine and related compounds, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a chlorine-ammonia displacement in the presence of a copper source.

专利号:US-2010016607-A1
优先权日:2006-12-11
标题:Process for the Synthesis of Highly Active Binary Metal Fluoride as a Fluorinating Agent for Aromatics
发明人：DOLBIER JR WILLIAM R; JANMANCHI KRISHNA MURTHY
权利人:UNIV FLORIDA
摘要:The subject invention relates to a process for the synthesis of highly active binary metal fluoride system for the fluorination of aromatic compounds. Fluorinated aromatic compounds are valuable synthons for the chemical synthesis of pharmaceutical drugs and novel polymers. Fluorobenzene is used to control carbon content in steel manufacturing, is an intermediate for pharmaceuticals, pesticides and other organic compounds. Fluorobenzene is typically produced by the reaction of aniline and sodium nitrite in the presence of hydrogen fluoride. The present invention relates to a process for the synthesis of highly active binary metal fluoride system consists of copper (II) fluoride and aluminum (III) fluoride for the fluorination of aromatic compounds in gas phase and recycling of the reagent, in situ, using O 2 and HF.

专利号:US-4801744-A
优先权日:1985-03-01
标 题 :Catalytic synthesis of urea from carbon monoxide and amine compound
发明人：HERMAN JEAN-JACQUES; LECLOUX ANDRE
权利人:SOLVAY
摘要:Process for the catalytic synthesis of nitrogen-containing organic compounds, comprising the reaction of carbon monoxide with at least one amino compound in a reaction mixture containing a catalyst based on selenium and a substituted pyridine. The process is particularly suitable for the synthesis of ureas and of their polymers.

专利号:US-2011245503-A1
优先权日:2008-11-28
标题 :Enantioselective synthesis of asymmetric beta-carboline intermediates
发明人：SANTOS LEONARDO; ESPINOZA MORAGA MARLENE; SHANKARAJAH NAGULA
权利人:UNIV TALCA
摘要:Described herein is a new asymmetric synthesis of imines to obtain β-carboline derivatives useful as key intermediate compounds for the synthesis of phosphodiesterase inhibitors using a new process with palladium or ruthenium hydride and/or nickel boride to reduce chiral intermediates. The use of chloroformate chiral auxiliaries is further described for the reduction and asymmetric hydrogenation of imines to obtain β-carboline derivatives and intermediate compounds used in the preparation thereof.

专利号:US-6271379-B1
优先权日:2000-03-08
标题:Intermediates useful for the synthesis of huperzine A
发明人：TUECKMANTEL WERNER; KOZIKOWSKI ALAN P
权利人:UNIV GEORGETOWN
摘要:Intermediates useful for the synthesis of huperzine A represented by the structures below, n and methods for their synthesis, wherein: n R 1 is lower alkyl, benzyl, or substituted benzyl; n X is a suitable leaving group; n Y is an electron withdrawing group that can subsequently be converted into an amino group; n one broken line is present as a carbon—carbon bond and the other broken line is absent, where the broken line forms an unconjugated carbon—carbon double bond, which double bond may be endocyclic whereby n is 3 or the double bond may be exocyclic whereby n is 2.

专利号:US-7276637-B2
优先权日:2002-08-02
标题:Synthesis of cyclohexanone derivatives
发明人：BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD
权利人:MERCK & CO INC
摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.