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CAS号565-60-6 3-甲基-2-戊醇(非对映异构... | CAS号77-74-7 3-甲基-3-戊醇 | CAS号108-11-2 甲基异丁基甲醇(MIBC) | CAS号565-67-3 2-甲基-3-戊醇 | CAS号760-21-4 2-乙基-1-丁烯 | CAS号625-27-4 2-甲基-2戊烯 | CAS号763-29-1 2-甲基-1-戊烯 | CAS号24319-08-2 3-iodo-3-methyl... | CAS号760-20-3 3-甲基-1-戊烯 | CAS号54509-73-8 ethene | CAS号355-42-0 全氟己烷 | CAS号355-04-4 2-三氟甲基-1,1,1,2,... | CAS号865-71-4 1,1,1,2,2,3,4,4... | CAS号1805-22-7 全氟甲基环戊烷 | CAS号112156-74-8 1,1,1,2,2,4,4,4... | CAS号77-74-7 3-甲基-3-戊醇 | CAS号96-14-0 3-甲基苯酚甲酯 | CAS号96-37-7 甲基环戊烷 | CAS号71-43-2 苯 | CAS号3404-63-5 2-乙基-1,3-丁二烯📜3-甲基-3-戊烯-2-酮置于甲烷磺酸,Ru/al,氢气体系中,130.0~150.0 °C,3.0 Mpa 条件下,反应 7.0H,反应生成 3-甲基-2-戊烯
参考文献:5-Sec-Butyl-2-(2,4-Dimethyl-Cyclohex-3-Enyl)-5-Methyl-[1,3]Dioxane And Process For Making The Same
标题:5-Sec-Butyl-2-(2,4-Dimethyl-Cyclohex-3-Enyl)-5-Methyl-[1,3]Dioxane And Process For Making The Same
摘要:本发明涉及5-Sec-丁基-2-(2,4-二甲基环己-3-烯基)-5-甲基-[1,3]二噁烷及其制备的新方法.
专利信息
专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人:HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.
专利号:US-2023183177-A1
优先权日:2020-04-24
标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
发明人:GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
权利人:PHARMAZELL GMBH
摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.
专利号:US-6951932-B2
优先权日:2001-10-25
标 题:Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
发明人:MOORMAN ALLAN R
权利人:KING PHARMACEUTICALS RES & DEV
摘要:The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine. Preferred methods of the invention include activating a guanosine compound followed by hydrolysis; alkylating the hydrolyzed compound with subsequent animation to provide a 2-aralkyloxyadenosine or a 2-alkoxyadenosine compound.
专利号:US-10570114-B2
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
发明人:FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
权利人:DOW AGROSCIENCES LLC
摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.
专利号:US-6372945-B1
优先权日:1995-06-07
标 题 :Process for the synthesis of vinyl sulfoxides
发明人:AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides
专利号:US-5606076-A
优先权日:1995-06-07
标 题 :Process for the synthesis of benzo[b]thiophenes
发明人:AIKINS JAMES A; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.