CAS: 6628-28-0; 2-Methyl-6-Ethoxyquinoline
该化合物是一种奎诺碱衍生物,其特征是六位和二位的乙氧基和甲基替代物,该化合物因其结构多功能性和作为复杂分子的构件潜力,对有机合成和制药研究具有兴趣,其quinoline核心提供了一个稳定的芳香框架,而乙氧基和甲基组则增强了溶性和再活性,使之适合进一步发挥功能.该化合物通常用于发展三环化合物,农用化学品和生物活性中间体.
- 英文名称2-Methyl-6-Ethoxyquinoline
- 中文名称2-甲基-6-乙氧基喹啉
- IUPAC名称6-ethoxy-2-methylquinoline
- 其它别名2-甲基-6-乙氧基喹啉/6-乙氧基-2-甲基喹啉; Ethyl 5-[(2,4-Dimethylphenyl)Carbamoyl]-4-Methyl-2-{[(4-Nitrophenyl)Carbonyl]Amino}Thiophene-3-Carboxylate
- CAS编号6628-28-0
- MFCD编号:MFCD00023987
- EINECS号:229-609-1
- FDA UNII编号:8XN28S08GI
- 分子式:C12H13NO分子量:187.24
- 产品CID: 1643906
- 产品分类有机原料→分子砌块→芳杂环类化合物→喹啉类化合物
相似化合物
1078-28-0 1378255-17-4 613-21-8物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07 & GHS05;
注释: Exclamation mark & Corrosion - 危险类别急性毒性 类别4(经口)
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼损伤 类别1 - 警示词Danger(危险)
- 危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H318 |造成严重眼损伤. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
- 安全声明26-36/37/39
- 危险类别码36/37/38
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号64-17-5 乙醇 | CAS号156-43-4 对氨基苯乙醚 | CAS号123-63-7 三聚乙醛 | CAS号123-73-9 2-丁烯醛 | CAS号75-07-0 乙醛 | CAS号61587-14-2 Formamide,N-(4-... | CAS号75-00-3 氯乙烷 | CAS号75-03-6 碘乙烷 | CAS号100063-12-5 2-Quinolinecarb... | CAS号104116-70-3 Quinaldic acid,... | CAS号74839-93-3 4-[2-(6-ethoxyq... | CAS号68516-69-8 6-ethoxy-1,2-di... | CAS号63151-41-7 6-ethoxy-1,2-di...合成工艺路线路线简述
- 合成目标产物 2-Methyl-6-Ethoxyquinoline 主要起始原料 Ethanol And Phenetidine
- (文献来源)合成步骤主要原料 Ethanol 和 Phenetidine
📜1-Vinyl-5-Methyl-2-(4-Ethoxyphenylazo)Pyrrole置于三氟乙酸体系中,用 异丙醇 作为反应溶剂,化学反应 6.0H,以26%的收率获得产物2-甲基-6-乙氧基喹啉
参考文献:Electrophilic Addition Of Alcohols To 1-Vinyl-2-Phenylazopyrroles And Unexpected Formation Of 2-Methylquinoline
标题:Electrophilic Addition Of Alcohols To 1-Vinyl-2-Phenylazopyrroles And Unexpected Formation Of 2-Methylquinoline
摘要:1-Vinyl-2-Phenylazopyrroles React With Alcohols In The Presence Of Acids Or Pdcl2 To Give 1-(1-Alkoxyethyl)2-Phenylazopyrroles In Up To 49% Yield. In The Presence Of Trifluoroacetic Acid 2-Methylquinoline Unexpectedly Formed (Yield Up To 26%) Involving Into The Reaction The Phenylazo And 1-Vinyl Groups.
DOI:10.1134/s1070428007100156
海关参考信息
- 2933310010-吡啶
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Co(III)-Catalyzed C-H Amidation Of Nitrogen-Containing Heterocycles With Dioxazolones Under Mild Conditions作者:Ankit Kumar Dhiman,Ankita Thakur,Inder Kumar,Rakesh Kumar,Upendra Sharma |发布日期:2020.7.17
摘要:A Cobalt(III)-Catalyzed C-8 Selective C-H Amidation Of Quinoline N-Oxide Using Dioxazolone As An Amidating Reagent Under Mild Conditions Is Disclosed. The Reaction Proceeds Efficiently With Excellent Functional Group Compatibility. The Utility Of The Current Method Is Demonstrated By Gram Scale Synthesis Of C-8 Amide Quinoline N-Oxide And By Converting This Amidated Product Into Functionalized Quinolines
合成参考文献
摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 72.
摘要:Albero, J.; García, H., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 583.
摘要:Sharma, U.; Parmar, D.; Sumit; Manisha, Science of Synthesis: Knowledge Updates, (2024) 2, 94.
摘要:Sharma, U.; Parmar, D.; Sumit; Manisha, Science of Synthesis: Knowledge Updates, (2024) 2, 39.
摘要:Sharma, U.; Parmar, D.; Sumit; Manisha, Science of Synthesis: Knowledge Updates, (2024) 2, 90.
📝 需求与反馈
尽可能描述清楚需求与问题信息
