CAS: 4628-39-1; 2-(2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-4-yl)Acetic Acid

该化合物是一种环环状有机化合物,其特点是具有湿环状结构,具有四氢结构,表明其含有饱和环状系统,有助于其稳定性和再活性,结构中存在两个碳基组(二氧化物),表明其可能表现出显著的再活动,特别是在核生殖反应中.此外,乙酸酶表明其具有酸性,可影响其溶性以及与其他化学物种的相互作用.该化合物可能因其潜在的生物活动而对医药化学感兴趣,因为其潜在的生物活动,因为经常会探讨丙酰胺衍生物在医药化学中的角色.其物理特性,如熔点,沸点和溶性,将取决于样品的具体条件和纯度.

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CAS号77-92-9 柠檬酸 | CAS号65-86-1 乳清酸

合成工艺路线路线简述

    📜柠檬酸置于硫酸,三氧化硫体系中,化学反应生成 尿嘧啶-4-乙酸
    参考文献:Drehmann; Born,Journal Fuer Praktische Chemie (Leipzig),1958,Vol. <4> 5,P. 200,206
    标题:Drehmann; Born,Journal Fuer Praktische Chemie (Leipzig),1958,Vol. <4> 5,P. 200,206

    海关参考信息

    专利信息


    专利号:US-8273403-B2
    优先权日:2002-05-10
    标题 :Generation of surface coating diversity
    发明人:BARDEN MICHAEL C; KAMBOURIS PETER A
    权利人:BARDEN MICHAEL C; KAMBOURIS PETER A; BIO LAYER PTY LTD
    摘要:This invention relates to a surface discovery system and high-throughput combinatorial synthesis methods for generating large numbers of diverse surface coatings on solid substrates. The system is built upon a synthon which comprises at least three elements: a chemical backbone coating on the solid substrate that comprises a copolymer (B) of at least one passive constituent (P) and at least one active constituent (A); a spacer unit (S) separating the backbone from a functional group; and a functional group (F). The methods comprise the following steps: 1) selecting a plurality of synthons so that each synthon has at least two points of diversity selected from P, A, S and F; 2) applying copolymer B onto a substrate; and 3) attaching a combination of S and F to constituent A of copolymer B. Steps 2) and 3) are performed such that different synthons are generated on localized regions of the substrate.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/j.bmcl.2009.11.017
    摘要:Roy AC, Lunn FA, Bearne SL. Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. Bioorganic & Medicinal Chemistry Letters. 2010 Jan;20(1):141–4. doi: 10.1016/j.bmcl.2009.11.017.
    摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
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