CAS: 142-84-7; Dipropylamine

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CAS号107-12-0 丙腈 | CAS号25070-76-2 N-(benzyloxycar... | CAS号108-03-2 1-硝基丙烷 | CAS号107-10-8 丙胺 | CAS号54509-73-8 ethene | CAS号201230-82-2 carbon monoxide | CAS号79-05-0 丙酰胺 | CAS号75162-84-4 4-methyl-N,N-di... | CAS号141-43-5 2-氨基乙醇 | CAS号628-91-1 di-n-propylzinc | CAS号106835-04-5 3-bromo-N,N-dip... | CAS号106332-42-7 4-(dipropylamin... | CAS号105538-52-1 4-(dipropylamin... | CAS号1116-24-1 N,N-二丙基乙酰胺 | CAS号100-01-6 对硝基苯胺 | CAS号77486-47-6 N'-(4-nitrophen... | CAS号1114-59-6 N,N-Dipropylpro... | CAS号3405-42-3 N-甲基二丙胺 | CAS号54491-43-9 3-phenylsulfany... | CAS号120517-33-1 2,3-bis(methyls...

丙腈置于5%-Palladium/activated Carbon,甲酸铵体系中,用 乙醇 用作溶剂,化学反应生成二正丙胺
参考文献:在质子惰性溶剂中由腈有效合成叔胺
标题:在质子惰性溶剂中由腈有效合成叔胺
摘要:叔胺被广泛用作非亲核质子清除剂,用于许多有机转化.在本文中,我们报道了在非均相钯催化剂和非质子溶剂中二氢源的存在下,由其相应的烷基腈有效合成叔烷基胺的方法.该反应是原子经济的,条件温和,分离的收率实际上是定量的.胺烷基化程度显示出一定的溶剂依赖性.在质子惰性极性溶剂(例如乙醇或甲醇)中,该反应提供了以仲烷基胺为主要产物的产物混合物.
Doi:10.1016/j.Tetlet.2012.06.044

专利信息

专利号:US-11161827-B2
优先权日:2019-04-05
标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
发明人：Zhang xiao-xiang; Lang kai
权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-8138330-B2
优先权日:2006-09-11
标 题 :Process for the synthesis of oligonucleotides
发明人：LEUCK MICHAEL; WOLTER ANDREAS; STUMPE ALFRED
权利人:LEUCK MICHAEL; WOLTER ANDREAS; STUMPE ALFRED; SIGMA ALDRICH CO LLC
摘要:The present invention discloses novel methods for the synthesis of oligonucleotides with nucleoside phosphoramidites on solid supports. The methods comprise the stepwise chain assembly of oligonucleotides on supports with 5′-acyl phosphoramidites. The synthesis cycles consist of a front end deprotection step which is conducted with a solution of a primary amine or a phenolate, a phosphoramidite coupling step with a 5′-acyl nucleoside phosphoramidite in the presence of an activator, a phosphite oxidation step and an optional capping step. The novel methods improve the quality of synthetic oligonucleotides due to the irreversibility of the front end deprotection step, which prevents the formation of deletion sequences, and due to the avoidance of acidic reagents in the synthesis cycles, which prevent the formation of depurination side products. The invention further discloses novel nucleoside phosphoramidite compositions wherein the phosphoramidites carry acyl front end protective groups which are cleavable with primary amines or phenolates. The invention is applicable to the synthesis of oligodeoxyribonucleotides, oligoribonucleotides and oligonucleotides with modifications in their sugar or phosphate groups.

专利号:US-6821486-B1
优先权日:1997-02-20
标 题:Multiautoclave for combinatorial synthesis of zeolites and other materials
发明人：AKPORIAYE DUNCAN; DAHL IVAR MARTIN; KARLSSON ARNE; WENDELBO RUNE
权利人:SINVENT AS
摘要:The invention relates to a multi-autoclave and details of its design, a method for automated synthesis of zeolites in the multi-autoclave, and furthermore, to applications of the multi-autoclave for an automated synthesis which is optimized simultaneously with regard to several synthesis parameters in the synthesis of zeolites. The multi-autoclave consists typically of a pressure vessel/autoclave having from 10 to 10,000 small, separated chambers lined with an inert material, with each chamber typically having a volume of 0.2-2 ml. The chambers preferably are formed as through-going perforations in a central block and the perforations are sealed by balls, septa, stoppers or such which are placed at the bottom and top of each through-going perforation. Metal plates are placed over and under the central block so that a closing mechanism is pressed against the edges of the perforations with sufficient load to enable the chambers to be filled with aqueous mixtures and to be heated to 200° C. without the occurrence of leakage. Top and bottom plates and closing mechanisms can be integrated so that all the perforations are sealed simultaneously when these are placed at the top and bottom sides of the central block.

专利号:US-7247287-B2
优先权日:2003-06-11
标 题 :Synthesis of aluminophosphates and silicoaluminophosphates
发明人：CAO GUANG; SHAH MATU J
权利人:EXXONMOBIL CHEM PATENTS INC
摘要:The invention is directed to a method of synthesising silicoaluminophosphate and aluminophosphate molecular sieves using synthesis templates that contain at least one template of general formula R 1 R 2 N—R 3 , wherein R 1 and R 2 are independently selected from the group consisting of alkyl groups having from 1 to 3 carbon atoms and hydroxyalkyl groups having from 1 to 3 carbon atoms; R 3 is selected from the group consisting of 4- to 8-membered cycloalkyl groups, optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms, and 4- to 8-membered heterocyclic groups having from 1 to 3 heteroatoms, said heterocyclic groups being optionally substituted by 1 to 3 alkyl groups having from 1 to 3 carbon atoms and the heteroatoms in said heterocyclic groups being selected from the group consisting of O, N, and S. In particular, the present invention relates to the synthesis of silicoaluminophosphate molecular sieves of the CHA framework type having a low silicon to aluminium atomic ratio.

专利号:US-6540970-B1
优先权日:1999-11-18
标题:Method for the synthesis of molecular sieves
发明人：STROHMAIER KARL G; VAUGHAN DAVID E W
权利人:EXXON MOBIL CHEM PATENTS INC
摘要:The present invention provides a method for the synthesis of MeAPO molecular sieves which includes the following steps: providing a source of alumina, a source of phosphorus, water, and a template suitable for forming a MeAPO molecular sieve; providing a source of metal (Me) including metal particles, the metal particles measuring, in their largest dimension, equal to or less than five nanometers; providing a water soluble organic solvent capable of solubilizing the source of metal; forming a synthesis mixture from the source of alumina, the source of phosphorus, the water, the template, the source of metal, and the solvent; and forming a MeAPO molecular sieve from the synthesis mixture.

专利号:US-2007259917-A1
优先权日:2006-04-24
标题 :Processes for the synthesis of 3-isobutylglutaric acid
发明人：KANSAL VINOD K; CHAURASIA BRIJNATH P; PATEL HITESH K; SHELKE SHIVAJI H; MORE YOGESH P
权利人:KANSAL VINOD K; CHAURASIA BRIJNATH P; PATEL HITESH K; SHELKE SHIVAJI H; MORE YOGESH P
摘要:Provided are processes for the synthesis of 3-isobutylglutaric acid, an intermediate in the synthesis of (S)-Pregabalin.