CAS: 869-02-3; 2-Cyano-5-Methylhex-2-Enoic Acid

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      专利号:WO-2004011474-A1
      优先权日:2002-07-31
      标题:Universal support media for synthesis of oligomeric compounds
      发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
      权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
      摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

      专利号:US-6653468-B1
      优先权日:2002-07-31
      标 题 :Universal support media for synthesis of oligomeric compounds
      发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH
      权利人:ISIS PHARMACEUTICALS INC
      摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

      专利号:US-4567265-A
      优先权日:1984-01-16
      标题:Cyclopropanoid cyanoesters and method of making same
      发明人:BABLER JAMES H
      权利人:UNIV LOYOLA CHICAGO
      摘要:Cyclopropanoid cyanoesters of the formula: where R' is -CH3 or -CH2CH3, and A is (a) -H, or (b) A, B represents an aliphatic group joined to a carbon atom on the cyclopropanoid ring, thereby forming a spiro group, A, B being selected from structures having the formula: (i) -(CH2)n-, wherein n=3, 4, or 5, and (ii) -(CH2)2-Y-(CH2)2-, wherein Y is NCH3, O, or S); and, when A is -H, B is selected from the group consisting of: +TR (CH3)2CHCH2. are disclosed. These compositions are useful in the synthesis of pyrethroids. A process for synthesis of cyclopropanoid cyanoesters by reacting 2-nitropropane with cyanoesters of the general formula: is also disclosed and claimed.

      专利号:EP-1789107-B1
      优先权日:2004-08-30
      标题 :Medical stent provided with inhibitors of atp synthesis
      发明人:POPOWSKI YOURI
      权利人:INTERSTITIAL THERAPEUTICS
      摘要:The present invention relates to a stent provided with a composition comprising at least one type of inhibitor of ATP synthesis optionally together with at least one inhibitor of the pentose phosphate pathway (PPP) for use in treating stenosis and preventing restenosis in vascular ducts, and for use in treating cancerous tumours present in ducts, resectioned cavities and scars, and for use in treating any disorder arising from the proliferation of cells in ducts or cavities.

      专利号:US-8283423-B2
      优先权日:2006-09-29
      标题:Polymer synthetic technique
      发明人:SWAGER TIMOTHY M; AMARA JOHN P
      权利人:SWAGER TIMOTHY M; AMARA JOHN P; MASSACHUSETTS INST TECHNOLOGY
      摘要:The present invention generally relates to methods for the synthesis of species including monomers and polymers. Methods of the invention comprise the use of chemical techniques including metathesis chemistry to synthesize, for example, monomers and/or polymers with desired functional groups.

      专利号:WO-0040532-A2
      优先权日:1998-12-31
      标 题:Synthesis of dihydrohonokiol compositions

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      ✅ COA系统入驻 | 共享模式

      合成参考文献


      参考文献:10.1016/j.ijpharm.2006.07.006
      摘要:Hillaireau H, Le Doan T, Besnard M, Chacun H, Janin J, Couvreur P. Encapsulation of antiviral nucleotide analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules. International Journal of Pharmaceutics. 2006 Oct;324(1):37–42. doi: 10.1016/j.ijpharm.2006.07.006.
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