CAS: 7252-86-0; (4-(Tert-Butyl)Phenyl)(Methyl)Sulfane

该化合物是一种芳香化合物,其特征为以苯环替换的苯环,代之以异丁基组和甲基硫基组.在标准条件下,乙基丁基混合物相对稳定,但可发生典型的芳香化合物反应,包括电药用替代物.其应用可能包括作为有机合成的中间体或作为调味剂使用,尽管其具体用途各不相同.应参考安全数据,因为含有硫磺的化合物可构成健康风险和环境关切.

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2396-68-1 70026-35-6 91907-08-3

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上下游产品

4-t-butylbenzenethiol dimethyl sulfate methyl iodide 1-bromo-4-tert-butylbenzene1-(tert-butyl)-4-(methylsulfonyl)benzene p-tert.-Butyl-cumol 1-(tert-butyl)-4-propylbenzene tert-butylbenzene

合成工艺路线路线简述

    📜叔丁基苯置于三氟甲磺酸酐,Sodium Carbonate,Potassium Carbonate体系中,用 二氯甲烷,二甲基亚砜,乙腈 作为反应溶剂,化学反应 25.0H,反应生成 对叔丁基苄硫醇
    参考文献:通过电子供体-受体复合物在可见光驱动下合成芳基黄原酸酯和芳基二硫代氨基甲酸酯
    标题:通过电子供体-受体复合物在可见光驱动下合成芳基黄原酸酯和芳基二硫代氨基甲酸酯
    摘要:在此,我们报告了一种简便,高效且实用的方案,该方案能够通过光活化电子供体-受体复合物从功能化的二苯并噻吩盐制备芳基黄原酸盐和芳基二硫代氨基甲酸盐.这种温和,无金属的方法操作简单,具有广泛的底物范围和潜在的用途,可用于天然产物和药物的后期功能化.最后,该方法还重新定义了leuckart苯硫酚反应的底物范围和反应途径.
    DOI:10.1021/acs.Orglett.2C03736

    海关参考信息

    专利信息


    专利号:US-11661406-B2
    优先权日:2018-08-13
    标 题 :Method for producing intermediate useful for synthesis of SGLT inhibitor
    发明人:LI QING RI; YOON HEE KYOON
    权利人:DAEWOONG PHARMACEUTICAL CO LTD
    摘要:A method of preparing an intermediate useful for the synthesis of a diphenylmethane derivative that can be used as an SGLT inhibitor is described. A method of synthesizing a compound of Formula 7 can address problems of existing synthesis processes requiring the synthesis of the Grignard reagent and management of related substances. In addition, the method can minimize the generation of related substances, and thus does not require reprocessing of reaction products, thereby simplifying the process. Accordingly, the production yield of a diphenylmethane derivative can be maximized.

    专利号:US-11192908-B2
    优先权日:2018-08-17
    标题:Octamolybdate compounds exhibiting bright emission
    发明人:DANIELS STEVEN; PICKETT NIGEL; SAVJANI NICKY; GAVRILIUC VIRGIL
    权利人:NANOCO 2D MAT LIMITED; UNIV MANCHESTER
    摘要:Methods for the synthesis of a polyoxometalate compounds include heating a metal precursor in the presence of an organic salt. The polyoxometalate compounds produced herein display high photoluminescence quantum yields and photoluminescence maximums in the blue and/or violet regions of the electromagnetic spectrum.

    专利号:US-2021292291-A1
    优先权日:2018-08-13
    标 题:Method for producing intermediate useful for synthesis of sglt inhibitor

    专利号:US-9868718-B2
    优先权日:2006-01-06
    标 题 :Cycloalkylamines as monoamine reuptake inhibitors
    发明人:SHAO LIMING; WANG FENGJIANG; MALCOLM SCOTT CHRISTOPHER; HEWITT MICHAEL CHARLES; BUSH LARRY R; MA JIANGUO; VARNEY MARK A; CAMPBELL UNA; ENGEL SHARON RAE; HARDY LARRY WENDELL; KOCH PATRICK; CAMPBELL JOHN E
    权利人:SUNOVION PHARMACEUTICALS INC
    摘要:The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Cristau, H.-J.; Virieux, D., Science of Synthesis, (2007) 31, 1964.
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