二氯二甲基硅烷置于水体系中,化学反应生成 十甲基环五硅氧烷 参考文献:Patnode; Wilcock,Journal Of The American Chemical Society,1946,Vol. 68,P. 360,363 标题:Patnode; Wilcock,Journal Of The American Chemical Society,1946,Vol. 68,P. 360,363
专利信息
专利号:US-2005112158-A1 优先权日:2003-11-17 标 题 :Method for synthesis of silylated ascorbic acid derivatives 发明人:TERRY W L JR; LEGROW GARY E; LITTAU CHERYL 权利人:CLARIANT INTERNATINONAL LTD 摘要:A compound of Formula (I), as defined in the specification, and a method for its synthesis. The method includes providing an inert environment, minimizing exposure of the reaction environment to visible light and reacting ascorbic acid with solvent and a compound of the Formula (II), as defined in the specification. The method of the present invention produces increased yields and a compound having increased stability and the same or greater bioactivity than ascorbic acid. The compound formed by the method of the present invention is capable for use in anhydrous cosmetic, dermatological and pharmaceutical compositions as an active agent for combating aging of the skin and improving its aesthetic appearance.
专利号:US-9982005-B2 优先权日:2013-04-04 标 题 :Macrolides and methods of their preparation and use 发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG 权利人:HARVARD COLLEGE 摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.
专利号:WO-2007094533-A1 优先权日:2006-02-17 标题:Composition for inhibiting collagen degradation and promoting collagen synthesis comprising emodin 发明人:PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK 权利人:BIOSPECTRUM INC; PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK 摘要:Disclosed is a composition, comprising emodin, for inhibiting collagen degradation and promoting collagen synthesis. The composition stimulates cell regeneration by promoting the synthesis of collagen by normal fibroblasts, alleviates wrinkles, and imparts the skin with elasticity. Also, the composition can be used as a preparation for external use for skin, such as cosmetics.
专利号:US-2012094919-A1 优先权日:2009-03-16 标题 :Use of tripeptides 发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.
专利号:EP-1721601-A1 优先权日:2005-05-11 标 题 :Use of taurine for enhancing lipid synthesis in the epidermis 发明人:DOERING THOMAS; WALDMANN-LAUE MARIANNE; WADLE ARMIN; ANDERHEGGEN BERND 权利人:HENKEL KGAA 摘要:The present invention is the use of taurine for stimulating the epidermal synthesis of barrier lipids.
专利号:US-9149659-B2 优先权日:2012-11-14 标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER 权利人:COTY GERMANY GMBH 摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
[参考文献]: Seon Ju Yeo, Et Al. Angle- And Strain-Independent Coloured Free-Standing Films Incorporating Non-Spherical Colloidal Photonic Crystals. Soft Matter. 2015 Feb 28;11(8):1582-8.
合成参考文献
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