CAS: 4887-88-1; 5-Bromo-1H-Benzo[d]Imidazole

相似化合物

942590-05-8 1006899-77-9 74545-26-9

上下游产品

5-溴-1,3-二氢-2H-苯并咪唑-2-硫酮 5-Bromo-1H-Benzo[d]Imidazole-2(3H)-Thione 68468-39-3
苯并咪唑 Benzoimidazole 51-17-2

苯并咪唑置于sulfonic Acid Functionalized Silica N-溴代丁二酰亚胺(Nbs)体系中,用 乙醚,乙腈 作为反应溶剂,化学反应 3.0H,以77%的收率获得产物5-溴-1H-苯并咪唑
参考文献:An Efficient,Rapid And Regioselective Nuclear Bromination Of Aromatics And Heteroaromatics With Nbs Using Sulfonic-Acid-Functionalized Silica As A Heterogeneous Recyclable Catalyst
标题:An Efficient,Rapid And Regioselective Nuclear Bromination Of Aromatics And Heteroaromatics With Nbs Using Sulfonic-Acid-Functionalized Silica As A Heterogeneous Recyclable Catalyst
摘要:A Simple,Efficient And Rapid Method Has Been Developed For High-Yielding Regioselective Nuclear Monobromination Of Aromatic And Heteroaromatic Compounds Using Nbs In The Presence Of Sulfonic-Acid-Functionalized Silica At Room Temperature. The Catalyst Works Under Heterogeneous Conditions And Can Be Recycled. (C) 2006 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2006.10.029

专利信息

专利号:US-8404670-B2
优先权日:2009-02-11
标题:Histamine H3 inverse agonists and antagonists and methods of use thereof
发明人：CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SPEAR KERRY L
权利人:CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SPEAR KERRY L; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:CN-107955020-A
优先权日:2017-12-05
标题 :One-pot synthesis of benzimidazoloxazinones catalyzed by copper salts

专利号:CN-111841638-A
优先权日:2019-04-30
标 题:Visible light catalyst and CO catalytic conversion thereof2Use of benzazepine for the synthesis of benzazepine

专利号:CN-111841638-B
优先权日:2019-04-30
标题 :Visible light catalyst and CO catalytic conversion thereof2Use of benzazepine for the synthesis of benzazepine

专利号:US-2013273461-A1
优先权日:2012-04-11
标题 :Synthesis of electrocatalysts using metal-organic framework materials

专利号:CN-109265403-B
优先权日:2018-11-02
标 题:Synthesis method of benzimidazole and derivatives thereof