CAS: 2117-11-5; 4-Pentyn-2-Ol

该化合物是在室温下无色液体,表现出一种特异味.已知该化合物在有机合成中的用途,特别是在生产各种化学中间体和药物方面.由于存在三重结合,该化合物的再活性因合成有机化学合成体而得到加强,使其成为一个有价值的建筑构件.安全考虑包括接触时的易燃性和潜在健康危害,需要适当的处理和储存措施.

结构式图片

相似化合物

4187-86-4 590-37-4 14898-79-4

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

propargyl magnesium bromide acetaldehyde propargyl bromide sodium acetylide (R,S)-4-Heptyn-2-ol 1,1-Diphenyl-2-hexin-1,5-diol -1-phenoxy-aethan1-1-Methyl-butin-(3)-yloxy-1-phenoxy-aethan -pentin-(1)-ol-(4)1-1-hydroxycyclohexyl-(1)-pentin-(1)-ol-(4)

合成工艺路线路线简述

    📜(Z)-1-Brommethylen-2-Methylcyclopropan置于乙醇,三乙胺体系中,化学反应生成4-戊炔-2-醇
    参考文献:Hammen,G. Et Al.,Chemische Berichte,1974,Vol. 107,P. 1676-1683
    标题:Hammen,G. Et Al.,Chemische Berichte,1974,Vol. 107,P. 1676-1683

    海关参考信息

    专利信息


    专利号:US-5637757-A
    优先权日:1995-04-11
    标 题 :One-pot synthesis of ring-brominated benzoate compounds
    发明人:HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
    权利人:GREAT LAKES CHEMICAL CORP
    摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

    专利号:US-10787576-B2
    优先权日:2015-04-30
    标 题 :Method for the preparation of a coating comprising oligomeric alkynes
    发明人:FRAUENRATH HOLGER; SCHRETTL STEPHEN; SCHULTE BJOERN; LETERRIER YVES
    权利人:ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO
    摘要:The invention relates to a method for the preparation of a coating comprising at least one coating layer on a substrate, the method comprising the steps of a. providing monomers of the type R—(N) x -(L) m -(Câ•?C) n -(L′) o -(N′) y —R′, wherein R is a head moiety, R′ is a tail moiety, (C≡C) n is an oligoyne moiety, L and L′ are linker moieties, N and N′ independently are branched or unbranched optionally substituted C 1 -C 25 alkyl moieties optionally containing 1 to 5 heteroatoms, x, m, o, and y are independently 0 or 1, n is 4 to 12, and wherein the head moiety allows for an interaction with the surface of the substrate; b. bringing the monomers into contact with the substrate wherein the interaction of the head moieties of the monomers with the surface of the substrate induces at least a part of the monomers to align in a defined manner thereby forming a film on the surface and bringing the oligoyne moieties of the monomers into close contact with each other; c. inducing a reaction between oligoyne moieties by providing an external stimulus so as to at least partially cross-link the aligned monomers, thereby forming a coating layer on the substrate. The invention further relates to a coating obtainable according to the method of the invention, the use of a coating obtainable according to the method of the invention, a substrate comprising a coating obtainable according to the invention and the use of solid substrate. The invention further relates to a method for the synthesis ofthe monomers according to the invention.

    专利号:US-7999090-B2
    优先权日:2000-07-07
    标 题:Fungal cell wall synthesis gene
    发明人:TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
    权利人:EISAI R&D MAN CO LTD
    摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.

    专利号:CN-101365674-A
    优先权日:2005-07-21
    标题:Modulators of interleukin-1 and tumor necrosis factor alpha, synthesis of the modulators and methods of using the modulators

    专利号:US-6583315-B2
    优先权日:2000-12-23
    标 题:Process for preparing ethanebis(alkylphosphinic) acids
    发明人:SICKEN MARTIN; WEFERLING NORBERT; SCHMITZ HANS-PETER
    权利人:CLARIANT GMBH
    摘要:The invention relates to a process for preparing ethanebis(alkylphosphinic) acids by n a) reacting elemental yellow phosphorus with alkyl halides in the presence of alkali metal hydroxide or of alkaline earth metal hydroxide to give a mixture whose main constituents are the alkali metal salts and/or alkaline earth metal salts of alkylphosphonous, phosphorous, and hypophosphorous acid, n b) liberating alkylphosphonous, phosphorous, and hypophosphorous acid by adding mineral acids, and also at the same time precipitating the alkali metal ions and, respectively, alkaline earth metal ions in the form of their salt of the mineral acids, and then n c) esterifying the alkylphosphonous acid from the mixture of the alkylphosphonous, phosphorous, and hypophosphorous acid, n d) isolating the ester of alkylphosphonous acid from the mixture and hydrolyzing the same to give alkylphosphonous acid, and n e) preparing, from the alkylphosphonous acid, the corresponding ethanebis(alkylphosphinic) acid of the general formula (I) where R 1 and R 2 may be identical or different and are hydrogen, a carboxy group, a carboxylic acid derivative, an unsubstituted or substituted alkyl group having from 1 to 10 carbon atoms, phenyl, benzyl, or alkyl-substituted aromatics, and R 3 and R 4 are identical or different and are an unsubstituted or substituted alkyl group having from 2 to 20 carbon atoms, by free-radical-initiated reaction with alkynes, and also to the use of the ethanebis(alkylphosphinic) acids prepared by this process as starting material for preparing flame retardants and precursors for the synthesis of other phosphorus-containing compounds.

    专利号:WO-9632368-A1
    优先权日:1995-04-11
    标题:One-pot synthesis of ring-brominated benzoate compounds

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2014) 4, 63.
    摘要:Mérour, J.-Y.; Joseph, B., Science of Synthesis Knowledge Updates, (2016) 3, 399.
    摘要:Bartels, F.; Zimmer, R.; Christmann, M., Science of Synthesis Knowledge Updates, (2017) 3, 248.
    摘要:Yoo, W.-J.; Zhao, L.; Li, C.-J., Science of Synthesis: Multicomponent Reactions, (2013) 1, 203.
    摘要:Cheng, Z.; Zheng, Y.; Lu, Z., Science of Synthesis: Knowledge Updates, (2023) 1, 329.
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